OBJECTIVE To determine the cost effectiveness of two view mammography at incident screens. DESIGN Incremental cost effectiveness analyses recognising differences in current reading policy, based on effectiveness data from an observational study. SETTING Breast screening programmes in England and Wales. MAIN OUTCOME MEASURES Health service costs, cancers detected, incremental cost effectiv...

Assays monitoring P2Y12 platelet reactivity can accurately predict which patients will have a poor response to clopidogrel. We sought to determine the cost-effectiveness of using platelet reactivity assays (PRAs) to select a dual-antiplatelet regimen for patients with acute coronary syndrome. A hybrid decision tree Markov model was developed to determine the cost-effectiveness of universal clop...

OBJECTIVE The objective of this study was to compare the cost-effectiveness of various treatment modalities for hemiplegic shoulder pain. DESIGN A stage II economic evaluation. MAIN OUTCOME MEASURES Incremental cost effectiveness ratio of P-NMES, compared to slings and anti-inflammatory injections. RESULTS The incremental cost effectiveness ratio (ICER) of p-NMES, compared to anti-inflamm...

BACKGROUND Among patients in skilled nursing facilities for post-acute care, increased registered nurse, total licensed staff, and nurse assistant staffing is associated with a decreased rate of hospital transfer for selected diagnoses. However, the cost-effectiveness of increasing staffing to recommended levels is unknown. METHODS Using a Markov cohort simulation, we estimated the incrementa...

BACKGROUND Biologics are used for the treatment of inflammatory bowel diseases, Crohn´s disease and ulcerative colitis refractory to conventional treatment. In order to allocate healthcare spending efficiently, costly biologics for inflammatory bowel diseases are an important target for cost-effectiveness analyses. The aim of this study was to systemically review all published literature on the...

In assessing the cost-effectiveness of an intervention, the interpretation and handling of uncertainties of the traditional summary measure, the Incremental Cost Effectiveness Ratio (ICER), can be problematic. This is particularly the case with strategies towards universal health coverage in which the decision makers are typically concerned with coverage and equity issues. We explored the feasi...

OBJECTIVE Cost-effectiveness of a geriatric rehabilitation programme. DESIGN Economic evaluation alongside a randomized controlled trial. METHODS A total of 741 subjects with progressively decreasing functional ability and unspecific morbidity were randomly assigned to either an inpatient rehabilitation programme (intervention group) or standard care (control group). The difference between ...

PURPOSE To evaluate the incremental effectiveness and cost-effectiveness of a staged-based, computerized smoking cessation intervention relative to standard care in an urban managed care network of primary care physicians. DESIGN Decision-analytic model based on results of a randomized clinical trial. METHODOLOGY Patient outcomes and cost estimates were derived from clinical trial data. Eff...

PURPOSE To compare the costs, effectiveness, and cost-effectiveness of alternative treatment strategies for intermittent claudication. MATERIALS AND METHODS By combining data from the literature and original patient data, a Markov decision model was developed to evaluate the societal cost-effectiveness. Patients presented with previously untreated intermittent claudication, and treatment opti...