Metals, including iron, are present at high concentrations in amyloid plaques in individuals with Alzheimer’s disease, where they are also thought to be cofactors in generating oxidative stress and modulating amyloid formation. In this study, we present data from several Drosophila models of neurodegenerative proteinopathies indicating that the interaction between iron and amyloid beta peptide ...

The US Department of Agriculture and the US Department of Health and Human Services first developed the Dietary Guidelines for Americans in 1980 (1). The dietary guidelines provide advice to healthy Americans on food choices to promote healthy eating and reduce risk of disease. The dietary guidelines were updated in 1985, 1990, and 1995 to ensure their accurate interpretation of the most recent...

Synopsis A fundamental hypothesis for the evolution and maintenance of ornamental traits is that ornaments convey information to choosing females about the quality of prospective mates. A diverse array of ornaments (e.g., colors, morphological features, and behaviors) has been associated with a wide range of measures of individual quality, but decades of study of such indicator traits have fail...

Recall form last lectures that in prediction with expert advise, at each time t, the player plays at ∈ {e1, . . . , ek} and the adversary plays zt such that l(at, zt) ≤ 1 for some loss function. One example of such loss function is linear function l(at, zt) = a T t zt where |zt|∞ ≤ 1. Linear bandits are a more general setting where the player selects an action at ∈ A ⊂ Rk, where A is a convex s...

The efficacy of two doses of progesterone (P4), i.e. 350 and 300mg was evaluated in acycling crossbred ewes (50) during the autumn breeding season. Ewes were treated with intravaginal progesterone sponges with either 350mg or 300mg for 12 days. At standing estrus, ewes were hand mated (three cycles). Progesterone (350mg) gave a better (P<0.05) estrus response (75%), compared to 300mg dose (42%)...

The first step toward a modern understanding of fMRI resting brain activity was made by Bharat Biswal in 1995. This surprising, and at first rejected, discovery is now associated with many resting state networks, notably the famous default mode network (DMN). Resting state activity and DMN significantly reassessed our traditional beliefs and conventions about the functioning of the brain. For t...

Benjamin P Caughlin1, Bharat Bhushan2* and John Maddalozzo3 1Department of Otolaryngology Head and Neck Surgery, University of Illinois Hospital & Health Sciences System, Chicago, USA 2Department of Otolaryngology Head and Neck Surgery, Northwestern University Feinberg School of Medicine, Chicago, USA 3Division of Pediatric Otolaryngology, Ann & Robert H. Lurie Children’s Hospital of Chicago, C...

In this study, residual stresses from the electron beam additive manufacturing (EBAM) and selective laser melting (SLM) processes, due to repeated thermal cycles, were investigated. Residual stresses play a crucial role in part performance, and thus, it is critical to evaluate the process-induced residual stresses in AM parts. Ti-6Al-4V and Inconel 718 parts produced by EBAM and SLM, respective...

The electrochemical behavior of nickel, Inconel 600, Incoloy 800 and 316 stainless steel electrodes in different concentration of NaOH solution was investigated using the cyclic voltammetry technique (CV). All the curves in the anodic branch of the CV are characterized by anodic dissolution peak (A), passive region (B), anodic dissolution peak (C) before oxygen evolution. In the case of the cat...