background :subclinical hypothyroidism may adversely affect in vitro fertilization (ivf) outcomes. however the cutoff of thyroid-stimulating hormone (tsh) for diagnosis and treatment is controversal. the aim of this study was to find the association of clinical pregnancy rate with regard to tsh levels in women undergoing ivf.   methods: a historical cohort study of 816 infertile patients who un...

background: repeated implantation failure (rif) is defined as pregnancy failure after two to six times with at least ten high grade embryo transfer to uterus. a variety of causes have been anticipated for rif, including anatomical, autoimmune, genetics, endocrine and thrombotic anomalies. factors responsible for rif have important implication regarding treatment however in many couples a perfec...

background: various approaches have been used in the attempts to improve the quality of frozen–thawed mouse sperms. according to literatures, it seems that hyaluronic acid (ha) has an important role on the permeability and motility of sperms and their interaction with gametes. objective: for evaluation of ha supplementation on sperm characteristics and fertilization capability, we investigated ...

background: luteal phase support is mandatory in art (assisted reproductive technologies) for optimizing outcome, so the luteal phase is supported with either progesterone, addition of estradiol to progesterone, hcg or gonadotropin releasing hormone (gnrh) agonists. supplementation of luteal phase with progesterone is prescribed for women undergoing routine ivf treatment. objective: to compare ...

background: caffeine increases the camp production that stimulates spermatozoa movement. caffeine is also used for induction of in vitro acrosome reaction in mammalian spermatozoa, an important step in achieving fertilization. objective: the aim of this study was to assess the effect of caffeine on sperm's motility, vitality and laboratory fertilization rates in mouse in two t6 and m16 media. m...

background:   case: we discuss 3 clinical cases of tubo-ovarian abscess in women with endometriosis after oocyte retrieval despite antibiotic prophylaxis between 2004 and 2011 at our center, and discuss our experience in the context of earlier reports.   conclusion: it is unclear whether antibiotic prophylaxis is necessary in these women, and which antibiotic is best. only douching with povidon...

background: the selection of blastocyst warmed for transfer is based on pre-freeze morphology in vitrified-warmed single blastocyst transfer cycles. but, it is controversial which parameter of blastocyst morphology most closely related to the clinical outcomes. objective: to estimate the effect of blastocoele expansion, trophectoderm (te) morphology grade, and inner cell mass (icm) morphology g...

background: vitrification has proven to be more effective than slow freezing methods to cryopreserve mammalian oocytes. the objectives of this study were to evaluate the effects of vitrification on immature and in vitro matured, denuded and cumulus compact goat oocytes and their subsequent fertilization. methods: oocytes were either cryopreserved as immature cumulus compact (imcc) (n=98 exp 1; ...

background: it is important to protect oocytes and embryos from oxidative stress in the culture medium. melatonin has been shown to be a direct free radical scavenger. objective: effect of melatonin during in vitro oocyte maturation, fertilization and embryo development of mouse oocytes was evaluated. materials and methods: oocytes from supper-ovulated mouse were divided to two groups: cumulus ...

BACKGROUND The aim of this study is to examine the effect of the embryo transfer (ET) day on clinical pregnancy success rates in in vitro fertilization-ET (IVF-ET) cycles. MATERIALS AND METHODS In this retrospective study, we divided patients with infertility who underwent IVF-ET with fresh embryos into two groups depending on whether the ET was performed on weekdays or weekends. The main out...