background candida species are normal microflora of  oral cavity, vagina, and gastrointestinal  tract. they are the third most prevalent cause of pediatric health care–associated  bloodstream fungal infection. this study aimed to provide an epidemiological feature of candidiasis and also presents an antifungal susceptibility profile of clinical candida isolates among children. materials and met...

Antifungal susceptibility tests are performed on fungi that cause disease, especially if they belong to a species exhibiting resistance to commonly used antifungal agents. Antifungal susceptibility testing is also important for resistance surveillance, for epidemiological studies and for comparing the in-vitro activity of new and existing agents. Dilution methods are used to establish the MICs ...

In vitro susceptibility of 58 isolates of Pichia anomala to five antifungal drugs using two broth microdilution methods (CLSI and EUCAST) was analyzed. Low susceptibility to itraconazole was observed. Fluconazole, voriconazole, amphotericin B, and caspofungin showed good antifungal activity, although relatively high drug concentrations were necessary to inhibit the isolates.

conclusions the monitoring of antifungal susceptibilities of candida species isolated from clinical sources is highly recommended for the efficient management of patients. moreover, the trailing effect should be taken into consideration once the interpretation of the results is intended. results among the tested antifungal drugs in this study, the highest rate of resistance was observed against...

background and purpose: candida species are the most common organisms involved in superficial fungal infections, worldwide. although econazole is among the most frequently used topical formulations for the treatment of candidiasis, no information is available regarding the susceptibility profiles of candida species in iran. materials and methods: in vitro susceptibility of 100 clinical candida ...

The in vitro antifungal susceptibility of 636 Candida bloodstream isolates collected from 15 tertiary hospitals in Korea was determined using the Vitek-2 yeast susceptibility system (bioMérieux, France). Overall susceptibility rates were 98.1%, 95.9%, 99.1%, and 97.3% for amphotericin B, fluconazole, voriconazole, and flucytosine, respectively. The results show that the rates of resistance to 4...

background : the aim of the present study was to evaluate the effects of metronidazole and albendazole against clinical isolates of giardia lamblia in vitro. methods : from all human samples of containing cysts, 10 isolates were successfully excysted in vitro . trophozites viability was assessed by eosine 0.1% and cultured axenically in tyi-s-33 modified medium supplemented with heat inactivate...

Members of the Cryptococcus neoformans/C. gattii species complex are grouped into eight molecular types, differing in their epidemiology, disease severity and geographic range. Recent in vitro antifungal susceptibility studies of isolates of the complex revealed contradictory results. The objective of the present study was to assess if this variation is random or correlates with different molec...

In this study, 34 clinical cerebrospinal fluid isolates of Cryptococcus neoformans were serotyped, and their in vitro susceptibilities to amphotericin B, fluconazole, and voriconazole were analyzed. Of these 34 isolates, serotype A was found in 29 isolates and serotype B in the other five. The voriconazole geometric mean MIC was significantly lower than the amphotericin B/antibiotic medium 3 ge...

We conducted in vitro experiments to evaluate the susceptibility of a clinical isolate of Cryptococcus neoformans to a wide range of concentrations of fluconazole. In vitro susceptibility was tested using broth macrodilution methods modified to provide a numeric count of viable organisms. The association between the quantitative in vitro response and fluconazole drug concentrations was estimate...