Background: Because implantation failure is more frequent, many methods have been suggested to improve the implantation; however, their results have been inconsistent. One of the most hopeful methods is local endometrial injury. To explore the possibility that local injury of the endometrium increases the incidence of implantation and pregnancy rate in the subsequent IVF cycle in patients havin...

the success rate of reproductive treatment methods depends on many different factors. the most important and discussed ones in the literature are maternal age, the causes of infertility, the ovarian response to stimulation, the influence of the male factor and sperm quality, embryo quality and the various uterine pathologies. some couples fail repeatedly after transferring good quality embryos ...

Implantation failure after IVF is one of the factors associated with a reduced chance of pregnancy for some patients. Assisted hatching methodologies are designed to facilitate the embryo's escape from the zona pellucida, and this strategy has been suggested as a means of improving pregnancy rates in patients with previous implantation failure. The aim of this prospective and randomized study w...

statement of the problem in recent decades, immediate implant placement has been proposed to eliminate undesirable consequences of conventional methods of delayed placement. in addition, because of the nature of this treatment method, a higher risk of complications such as infection and also higher failures rates may be expected purpose the aim of this study was to compare clinical outcomes of ...

Successful embryo implantation is a process which requires both a synchronous development and interaction between hatched blastocyst and endometrium. The process of implantation as a scheme is presented in Pic. 1, where the diagram shows a preimplantation stage of embryo and some important factors thought to be necessary for uterine receptivity: COX-2 (cyclooxygenase-2), EGF (epidermal growth f...

Objective(s): NOTCH signaling pathway is well known for its role in cell fate, cell survival, cell differentiation, and apoptosis. Some of the NOTCH signaling genes are critical for endometrial function and implantation in animals and appear to play a similar role in humans. The purpose of the current study was to investigate the potential roles of some main components of the NOTCH family in hu...

Background Implantation failure is the most important cause of recurrent in vitro fertilization/intra cytoplasmic sperm injection (IVF/ICSI) failure. Several reports suggest that intercourse during the peritransfer period might improve pregnancy rates. This study is designed to determine whether intercourse during the peritransfer period will improve pregnancy and implantation rates in patients...

BACKGROUND Bisphenol A (BPA) is a synthetic chemical widely used in the production of polycarbonate plastic and epoxy resins found in numerous consumer products. In experimental animals, BPA increases embryo implantation failure and reduces litter size. OBJECTIVE We evaluated the association of urinary BPA concentrations with implantation failure among women undergoing in vitro fertilization ...