osteogenesis imperfecta is a rare inherited connective tissue disorder with an expression that varies from mild to severe disease affecting bone, sclera and middle ear. fertility is preserved, especially in those patients with type 1. we present hereby a pregnant woman with osteogenesis imperfecta that had over 30 fractures in long bones and vertebrae. the object of this report was to determine...

The Design of Insurance Coverage for Medical Products under Imperfect Competition This paper studies the design of health insurance with ex post moral hazard, when there is imperfect competition in the market for the medical product. Various scenarios, such as monopoly pricing, price negotiation or horizontal differentiation are considered. The insurance contract specifies two types of copaymen...

Objective. This study assesses the impact of state policy reforms on health insurance coverage in the U.S. states considering three approaches to reform: consumer protection policies, policies relaxing regulation on insurance companies, and policies expanding public benefits. Methods. Using data collected from several publicly available sources, we estimate state insurance coverage using fixed-...

If animals are independently detected during surveys, many methods exist for estimating animal abundance despite detection probabilities <1. Common estimators include double-observer models, distance sampling models and combined double-observer and distance sampling models (known as mark-recapture-distance-sampling models; MRDS). When animals reside in groups, however, the assumption of indepen...

This article concerns construction of confidence intervals for the prevalence of a rare disease using Dorfman's pooled testing procedure when the disease status is classified with an imperfect biomarker. Such an interval can be derived by converting a confidence interval for the probability that a group is tested positive. Wald confidence intervals based on a normal approximation are shown to b...

the traditional economic production quantity (epq) model assumes that during the production process no imperfect item is produced. but in the real production system, due to imperfect production process or other factors, imperfect quality items may be produced. furthermore, it is well-known that the total production-inventory costs can be reduced by reworking the imperfect quality items produced...