The blood-brain barrier (BBB) serves as a highly selective barrier separating the central nervous system from the systemic circulation. Although contributing to neurological health, the BBB restricts the ability of drugs to reach their site of action and thus presents a major challenge to the treatment of neurological disorders. Advances in our understanding of the complexity of the BBB have fo...

The aim of this paper is to construct theoretical models which help to shed light on the recent criticisms of volatile investment flows. We do not make any empirical attempt to establish the existence or gauge the importance of the adverse effects of volatile investment flows nor do we make any implicit claims regarding the role of such flows in recent exchange rate crises. Instead we simply as...

s Invited speakers INTUITION, ANALYTIC THINKING, AND THE FEELING OF RIGHTNESS: A METACOGNITIVE REASONING THEORY Valerie Thompson, University of Saskatchewan Amongst educators and psychologists, questions of metacognition have garnered much attention, especially as they pertain to the domains of learning and memory. In this context, it is therefore somewhat surprising that relatively little is k...

Chronic kidney disease and chronic heart failure are now recognized as closely intertwined entities. The noxious interactions between the heart and kidney systems as part of the so-called cardiorenal syndrome is a matter of great concern for heart transplant candidates. Not only is chronic kidney disease a commonly associated comorbidity, but its detrimental effect on the outcome of heart trans...

Thermodynamic dislocation theory incorporating impediment by the grain boundaries is developed to analyze shear test of polycrystals. With a small set physics-based material parameters, we are able simulate stress–strain curves for load and its reversal, which consistent with experimental Thuillier Manach (Int J Plast 25:733–751, 2009). Representative distributions plastic slip under reversal p...

In this case report, a 36 year old female at 40 weeks' gestation is presented in whom large bilateral vestibular bulb masses were found on pelvic examination. The size of the masses was such as to cause concern that they may pose an impediment to normal parturition. Our pathological findings, management and results are presented.

in an international connection which different factors of legal relation were spread in different countries, bringing of several actions with the same object in different countries court was completely probable. each party with various reasons seeks litigation in a court which provides their interest in better way. however parallel litigation in it he same object impose burdensome charges on li...

The common perception of food as a mere attraction in tourism is challenged by stressing the complications and impediments experienced by tourists in the local culinary sphere in unfamiliar destinations, even when attracted to the local cuisine. Hygiene standards, health considerations, communication gaps, and the limited knowledge of tourists concerning the local cuisine are discussed, while t...