نتایج جستجو برای: immunologic marker
تعداد نتایج: 158841 فیلتر نتایج به سال:
abortion traditionally means miscarriage and is still known as a problem, which societies have been trying to reduce its rate by using legal means. despite the fact that pregnant women and fetuses have been historically supported; abortion was firstly criminalized in 1926 in iran, 20 years after establishment of modern legal system. during next 53 years this situation changed dramatically, t...
Cytotoxic lymphocyte antigen-4 (CTLA-4) blockade is an active immunotherapeutic strategy that is currently in clinical trials in cancer. There are several ongoing trials of anti-CTLA-4 in the metastatic setting of prostate cancer patients with reported clinical responses consisting of decreases in the prostate specific antigen (PSA) tumor marker for some patients. Immunologic markers that corre...
Colloidal gold was used as a marker for immunoelectron microscopy to localize lactoferrin (LF) and myeloperoxidase (MPO) in human peripheral blood neutrophils. Cells were reacted with monospecific antibodies against LF or MPO and then with gold-labeled antiglobulin. MPO cytochemistry was also associated with immunologic detection of LF. Immunologic labeling of thin sections after embedding in g...
BACKGROUND Activated phosphoinositide 3-kinase δ syndrome (APDS) is a recently described combined immunodeficiency resulting from gain-of-function mutations in PIK3CD, the gene encoding the catalytic subunit of phosphoinositide 3-kinase δ (PI3Kδ). OBJECTIVE We sought to review the clinical, immunologic, histopathologic, and radiologic features of APDS in a large genetically defined internatio...
Abstract Background and Objectives Transfusion of platelet has become one of the main treatments for thrombocytopenic patients to reduce the severity and frequency of bleeding consequences. Failure to attain the desired level of platelets in a patient following platelet transfusion is defined as platelet refractoriness. The purpose of present paper is to review and study the mechanisms involve...
primary immunodeficiency diseases (pid) consist of a group of long-term illnesses which had permanent psychiatric effects on the patients and their parents. this study was designed to find out the most important origins and aspects of stressor in parents of pid patients.to assess the impact of psychiatric aspects in parents of pid patients, a valid and reliable questionnaire was compiled ba...
Complement split products C3a and C4a are reportedly elevated in patients with acute Lyme disease. We have now examined these immunologic markers in patients with chronic Lyme disease compared to appropriate disease controls. The study population consisted of 29 healthy controls, 445 patients with chronic Lyme disease, 11 patients with systemic lupus erythematosus (SLE) and six patients with AI...
The immunologic surface markers on lymphocytes and clinical characteristics of 35 patients with established (stages 0-4) CLL with absolute lymphocyte counts greater than 15,000/cu mm were compared to those of a group of 25 patients with CLL in an early or preleukemic phase (counts of less than 15,000/cu mm). We found a monoclonal B cell proliferation in most cases in the latter group, in spite ...
Dysbalance in gut microbiota has been linked to increased microbial translocation, leading to chronic inflammation in HIV-patients, even under effective HAART. Moreover, microbial translocation is associated with insufficient reconstitution of CD4+T cells, and contributes to the pathogenesis of immunologic non-response. In a double-blind, randomised, placebo-controlled trial, we recently showed...
Serological diagnosis of an acute infection can be done by the demonstration of seroconversion and/or agent-specific IgM antibodies in the serum samples. Seroconversion describes 4 fold or more increase in antibody levels of the serum samples which is collected at the acute and convelescent phase (10-15 days intervals) of an infection. As the detection of seroconversion is time-consuming, the a...
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