BACKGROUND The objective of this study was to identify the prognostic indicators in patients with suspected myocarditis who underwent endomyocardial biopsy. METHODS AND RESULTS Between 1994 and 2007, 181 consecutive patients (age, 42+/-15 years) with clinically suspected viral myocarditis were enrolled and followed up for a mean of 59+/-42 months. Endomyocardial biopsies were studied for infl...

Tumor‑stroma interactions serve a crucial role in the development of colorectal cancer (CRC), which secreted protein acidic and rich cysteine (SPARC) has been implicated. Due to between stromal cells [mesenchymal stem (MSCs)], SPARC gene expression is markedly upregulated CRC cells. The present study investigated its potential as biomarker. Specifically, examined association clinicopathological...

Interleukin-1 activated chondrocytes have been identified in pig articular cartilage by immunolocalisation using a polyclonal antiserum recognising cytokine induced surface epitopes. Although chondrocytes with membrane staining were noted in all zones of the cartilage, only a proportion of the cells were positive within the range of antiserum dilution used (1:100-1:2000). Maximum staining was f...

The proliferative activity and growth pattern of 20 seminomas were determined immunohistologically with the monoclonal antibody Ki-67. A growth fraction of tumour cells between 50 and 80% was found in seminomas with an almost even distribution of proliferating cells in all sections, regardless of tumour size. There was a slight tendency towards a greater growth fraction in tumours at an advance...

Uterine natural killer (uNK) cells, a specific type of (NK) are important cells at the foeto-maternal interface in humans as well mice. uNK part innate lymphoid group 1. Especially mouse, but also rat, many vivo studies have been performed to evaluate role placental development. These shown that not indispensable pregnancy, they play an optimal decidual angiogenesis early trophoblast invasion a...