نتایج جستجو برای: immune mediated thrombocytopenia

تعداد نتایج: 656572  

2016
Yu-Chen Chen Lang-Ming Chi Kuan-Chih Chow Shiow-Her Chiou Yi-Hsin Fan Shu-Peng Ho Yu-Chen Hsu Yu-Chyi Hwang Meng-Xing Wu Wei-Ming Lee Shiun-Long Lin Chau-Loong Tsang Frank Chiahung Mao

BACKGROUND In humans, the presence of antiphospholipid antibodies (aPL) is frequently found in immune thrombocytopenia. The present study investigated whether aPL and any aPL subtypes are associated with canine thrombocytopenia, in particular, immune-mediated thrombocytopenia (immune thrombocytopenia) that usually manifests with severe thrombocytopenia. RESULTS Sera were collected from 64 out...

Journal: :Toxicology 2005
Richard H Aster

Drugs can induce thrombocytopenia by several mechanisms, including marrow suppression and destruction of platelets in the peripheral blood by non-immune and immune mechanisms. We will review here current understanding of the immune mechanisms by which drugs promote immune-mediated platelet destruction resulting in thrombocytopenia.

Journal: :iranian journal of basic medical sciences 0
muhammad umair department of pharmacology and toxicology, university of veterinary and animal sciences, lahore, pakistan aqeel javeed department of pharmacology and toxicology, university of veterinary and animal sciences, lahore, pakistan aamir ghafoor university diagnostics laboratory, university of veterinary and animal sciences, lahore, pakistan muhammad ashraf department of pharmacology and toxicology, university of veterinary and animal sciences, lahore, pakistan

objective(s):gemifloxacin is a broad spectrum antibiotic and has shown excellent coverage against a wide variety of microorganisms. in this study, an attempt was made to evaluate the immunomodulatory potential of gemifloxacin in male swiss albino mice in vivo. materials and methods: three doses of gemifloxacin 25 mg/kg, 50 mg/kg and 75 mg/kg were used intraperitoneally (ip) for the evaluation o...

2013
Limei Michelle Poon Antonio Di Stasi Uday Popat Richard E Champlin Stefan O Ciurea

Delayed recovery of platelet count post allogeneic hematopoietic stem cell transplantation (allo-HSCT) has been associated with worse transplant outcomes. Thrombopoietic agents have been successfully used in immune mediated thrombocytopenia or thrombocytopenia from bone marrow failure syndromes; however, the experience regarding their use after allo-HSCT is limited. Here we report on the safety...

Journal: :Veterinary and comparative orthopaedics and traumatology : V.C.O.T 2014
M B Walton E Mardell M Spoor J Innes

A four-year-old, male Cocker Spaniel was presented for investigation of pelvic limb stiffness. There was palpable effusion of both tarsi, and analysis of synovial fluid from these joints indicated previous haemorrhage. After further investigation a diagnosis of idiopathic immune-mediated thrombocytopenia was made. The dog responded to treatment with prednisolone and azathioprine. To the authors...

2018

The use of heparin have increased in the last years in hospitalized both as prophylaxis and therapeutic. One of the encounter complications of heparin especially with unfractionated heparin though it can be seen with Low molecular weight heparin is thrombocytopenia which could be transient non immune or more badly the immune mediated type heparin induced thrombocytopenia (HIT). Heparin-induced ...

2018

The use of heparin have increased in the last years in hospitalized both as prophylaxis and therapeutic. One of the encounter complications of heparin especially with unfractionated heparin though it can be seen with Low molecular weight heparin is thrombocytopenia which could be transient non immune or more badly the immune mediated type heparin induced thrombocytopenia (HIT). Heparin-induced ...

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