A hemolytic transfusion reaction (HTR) is the accelerated clearance or lysis of transfused red cells because of immunologic incompatibility. Although they may at times have similar clinical presentations, HTR is distinguished from autoimmune hemolysis or nonimmune causes of shortened survival of transfused red cells. HTR may occur when antigen-positive red cells are transfused to a patient with...

Delayed hemolytic transfusion reactions continue to occur in spite of the use of all of the currently available techniques of antibody detection. Both low titers of the antibodies and dosage effects appear to contribute to the failure of detection. A rapid anamnestic response can occur with transfusion of the appropriate antigen. The clinical as well as the laboratory presentation of delayed he...

Background: Atypical hemolytic uremic syndrome (aHUS) is a life-threatening and scarce disorder characterized by acute renal failure and disease, non-immune microangiopathic hemolytic anemia and thrombocytopenia, leading to end-stage renal failure or death, and consequently maybe accompanying by extra renal manifestations. Case report: We reported aHUS accompanied by autoimmune hemolytic anemi...

Synonyms and related keywords: blood transfusions, blood products, acute hemolytic transfusion reactions, transfusion complications, blood product reactions, allergic transfusion reaction, blood type, circulatory volume overload, anaphylactic transfusion reaction, blood anaphylaxis, hemolytic reactions, allergic reactions, anaphylactic reaction, anaphylaxis, transfusion-related acute lung injur...

Background: Patients with thalassemia major require frequent blood transfusions. Blood transfusion can lead to the adverse reactions. Reporting and evaluating the transfusion reactions are among the goals of implementing the hemovigilance system to improve blood recipients’ safety. This study aimed to compare the transfusion reactions in the thalassemia patients before and after implementation ...

background: transfusion services rely on transfusion reaction reporting to provide patient care and protect the blood supply. unnecessary discontinuation of blood is a major wastage of scarce blood, as well as man, hours and funds. the aim of the present study was to describe the main characteristics of acute transfusion reactions reported in the 4 hospital of kermanshah university of medical s...

By LAWRENCE E. YOUNG, M.D., DONALD M. ERVIN, M.D., AND CHARLES L. YUILE, M.D. H EMOLYTIC transfusion reactions occur more frequently than is generally appreciated and their incidence can be expected to increase for some time as the distribution of blood is facilitated. Many are doubtless overlooked because the outward manifestations may not be particularly striking, especially in anesthetized p...

By LAWRENCE E. YOUNG, M.D., DONALD M. ERVIN, M.D., AND CHARLES L. YUILE, M.D. H EMOLYTIC transfusion reactions occur more frequently than is generally appreciated and their incidence can be expected to increase for some time as the distribution of blood is facilitated. Many are doubtless overlooked because the outward manifestations may not be particularly striking, especially in anesthetized p...