نتایج جستجو برای: immune dysfunction
تعداد نتایج: 415461 فیلتر نتایج به سال:
Systemic Lupus Erythematosus (SLE) is a chronic, life threatening systemic disorder that may affect multiple organs in the body. Dysfunction of the immune system, leading to over production of antibodies and immune complexes cause wide arrays of clinical feature. The classification criteria of SLE were updated in 2012. Treatment of SLE is individualized based on severity and extent of organ inv...
In the development of neuroinflammatory diseases, alterations of the blood brain barrier (BBB) represent key events. The integrity of the BBB is partially maintained by endothelia cells (ECs), since they actively limit the transmigration of immune cells. However, the factors that cause endothelial cells to develop an immune cell-permissive phenotype are poorly understood. In general, it has bee...
Mucormycosis, COVID-19, host-iron assimilation, novel therapy, SARS CoV-2, hypoxia, cytokine storm, ciliary dysfunction, thrombo-inflammation, microvascular coagulation, and exhaustion of immune response
An examination of the prevalence and phenotype of immune disorders in different ethnic groups may provide important clues to the etiopathogenesis of these disorders. Whilst still conjectural the restricted and somewhat unique polymorphisms of the MHC (and other genetic loci involving host defences) of the Australian Aborigines may provide an explanation for their apparent heightened susceptibil...
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