نتایج جستجو برای: imidazolide

تعداد نتایج: 66  

Journal: :American journal of respiratory and critical care medicine 2009
Narsa M Reddy Vegiraju Suryanaraya Melinda S Yates Steven R Kleeberger Paul M Hassoun Masayuki Yamamoto Karen T Liby Michael B Sporn Thomas W Kensler Sekhar P Reddy

RATIONALE Oxygen supplementation (e.g., hyperoxia) is used to support critically ill patients with noninfectious and infectious acute lung injury (ALI); however, hyperoxia exposure can potentially further contribute to and/or perpetuate preexisting ALI. Thus, developing novel therapeutic agents to minimize the side effects of hyperoxia is essential to improve the health of patients with severe ...

Journal: :RSC advances 2013
Marcin Ziemniak Mariusz Szabelski Maciej Lukaszewicz Anna Nowicka Edward Darzynkiewicz Robert E Rhoads Zbigniew Wieczorek Jacek Jemielity

We describe the synthesis and properties of five dinucleotide fluorescent cap analogues labelled at the ribose of the 7-methylguanosine moiety with either anthraniloyl (Ant) or N-methylanthraniloyl (Mant), which have been designed for the preparation of fluorescent mRNAs via transcription in vitro. Two of the analogues bear a methylene modification in the triphosphate bridge, providing resistan...

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