OBJECTIVE To analyze, through molecular biology, the diversity of the intestinal microbiota before and after resection of the ileocecal junction and reconstruction of intestinal transit with and without the creation of a neosphincter. METHODS Fourteen Wistar rats were divided into two groups: Group A (n = 7), submitted to resection of the ileocecal valve and end-to-end, single-layer ileocolic...

A 61-year-old man was being treated for poor nutritional status. He had been on weekly methotrexate 6 mg and daily tacrolimus 1 mg and prednisolone 18 mg for 8 years due to dermatomyositis. On further workup, he was initially detected to have ileocecal ulcer with subsequent development of diffuse miliary shadows on chest radiograph. He was diagnosed as having ileocecal with miliary tuberculosis...

Pyloric gland metaplasia of the ileocecal valve, in the setting of Crohn's disease, is an unusual clinical entity. Though its etiology and pathogenesis remains unclear, metaplastic changes have been associated with chronic inflammation and inflammatory bowel disease. Herein, we report a case of a 23-year-old male who presented for surveillance colonoscopy after being diagnosed with Crohn's dise...

I T HAS LONG BEEN MY IMPRESSION, together with others, that the state of competence of the ileocecal valve is the key to the radiographic picture of mechanical large bowel obstruction. 8~‘4~i9*2’ Continued observation has reinforced some of my previous conclusions. 27 At that time, I described three patterns of obstruction (Fig. 1). Type II obstruction, that associated with incompetence of the ...

BACKGROUND Ileocecal Tuberculosis (TB) is difficult to diagnose clinically as getting histological specimens means resorting to surgery, which is often hazardous and complicated in sick, anemic and emaciated patients with malabsortion syndrome. The present study was undertaken as an attempt to devise clinical criteria for diagnosis of ileocecal TB without resorting to invasive surgery. METHOD...

BACKGROUND/AIMS Postoperative endoscopic recurrence (PER) occurs in nearly 80% of patients 1 year after ileocecal resection in patients with Crohn's disease (CD). Biological agents were more effective in reducing the rates of PER in comparison with conventional therapy, in prospective trials. The aim of this study was to compare the PER rates of biological versus conventional therapy after ileo...

BACKGROUND Unexpected inflammatory cecal masses of uncertain etiology, encountered in the emergency surgical departments can be indistinguishable, and appropriate operative management of these cases is a dilemma for the surgeons. METHODS Over a 30-months period between January 2009 and June 2011, a series of 3032 patients who live in sub-urban underwent emergency surgery for clinical diagnosi...

OBJECTIVE The aim of this article was to determine whether serial transverse enteroplasty (STEP) and the creation of a new ileocecal valve in extreme short bowel syndrome (SBS) cases (<45 cm) is effective in intestinal adaptation and improvement of nutritional parameters and serum citrulline levels. PATIENTS AND METHODS We present 2 cases of SBS treated with STEP. Enterectomy was performed fo...