Objective The study aim was to compare interictal encephalographic (EEG) functional network topology between people with well-controlled idiopathic generalized epilepsy (WC-IGE) and drug-resistant IGE (DR-IGE). Methods Nineteen participants WC-IGE, 18 DR-IGE, 20 controls underwent a resting state, 64-channel EEG. An artifact-free epoch bandpass filtered into the frequency range of high low exte...

Background: Hyper IgE syndrome (HIES) is a rare primary immune deficiency, described as Job`s syndrome characterized by increased serum levels of IgE, eczema, recurrent cutaneous and pulmonary infections. In this paper, we presented a case of Hyper IgE syndrome.Case Presentation: A 16-year-old Iranian boy presented with a one year history of skin lesions in knees and elbows was diagnosed of pso...

Determining the normal range of Immunoglobulin E (IgE) in any population is important for diagnosis of allergic diseases. The aim of this study was to determine normal values of IgE in children living in Tehran. Two-handed and fifty six healthy children aged one month to 14 years were selected. These children had neither parasitic infections nor atopic disease. They were divided into six groups...

Background and Purpose: Although molds are regarded as the main fungal allergen sources, evidence indicates that spores of Basidiomycota including Agaricus bisporus (A. bisporus) can be also found at high concentrations in the environment and may cause as many respiratory allergies as molds. The aim of the present study was to evaluate specific immunoglobulin E (IgE) and immunoglobulin G (IgG) ...

ige-mediated cell signaling, induced by cross-linking of high affinity receptor for ige (fcεri) in the presence of antigen (ag), is a well known mechanism described for mast cell activation in allergy and hypersensitivity reactions, which induces a spectrum of cellular responses such as secretion and up-regulation of cell surface fcεri. although for several years  ige  binding  to  fcεri  was  ...

the efficacy of allergen immunotherapy for the treatment of allergic rhinoconjunctivitis with or without seasonal bronchial asthma and anaphylaxis caused by the sting of the hymenoptera class of insects has been clearly demonstrated in numerous well-designed, placebo-controlled trials. immunotherapy whether by subcutaneous injection of allergen extract or by oral/sublingual routes modifies peri...

Abstract Mast cells play a critical role in the effector phase of immediate hypersensitivity and allergic reactions. Propolis exerts multiple biological effects exhibits immunomodulatory antioxidant properties. However, its antidinitrophenyl (DNP) immunoglobulin E (IgE)-activated mast has not been investigated. In this study, we examined mechanism underlying inhibitory effect propolis (Unibee p...