Introduction Urticaria and angioedema lasting more than 6 weeks have been designated as chronic urticaria (CU). It encompasses two major subtypes: chronic spontaneous urticaria (CSU) (previously known as chronic idiopathic urticaria) (CIU) and chronic inducible urticaria. CSU has been defined as wheals and/or angioedema that are endogenous and independent of any external physical stimulus. It a...

BACKGROUND: Controlled trials have demonstrated the efficacy of antihistamines in the treatment of chronic idiopathic urticaria. Second-generation antihistamines are recommended as first-line therapy for chronic idiopathic urticaria. The purpose of this study was to determine the effect of desloratadine, a newer, nonsedating, second-generation antihistamine, on symptoms of chronic idiopathic ur...

Chronic urticaria is common and patients may present with transient eruption of itchy, eruthematous, edematous swellings of the dermis, which lasts more than six weeks. One type of chronic idiopathic urticaria, and part of it, is the chronic autoimmune urticaria. The chronic autoimmune urticaria is caused by high affinity of IgE receptors (anti-FcRI) and less frequently by anti-IgE autoantibodi...

Chronic urticaria (CU) is a skin condition characterized by the presence of intensively pruritic lesions occurring intermittently or continuously for more than 6 weeks. Because the cause(s) of CU are often not known, it is usually referred as chronic spontaneous urticaria (CSU) or chronic idiopathic urticaria (CIU). It affects 0.1%–0.3% of children. Moreover, solar urticaria (SU) is a rare chro...

Background: There are no studies assesing whether patients with idiopathic anaphylaxis are a heterogenous population Objective: A study has been carried out to assess whether clinical and functional differences (mast cell releasability) exist between two sub-types of Idiopathic Anaphylaxis (Generalized Idiopathic Anaphylaxis -IA-Gand Idiopathic Anaphylaxis with Angioedema -IA-A-). Methods: Pati...

Chronic urticaria is a prolonged disease with unknown etiology and management.in order to determine the association of helicobacter pylori(H.pylori) infection with chronic urticaria,a case-control study was carried out in this regard 95 chronic urticaria patients without any underlying etiology and 190 healthy individuals who were matched for age and sex were evaluated by-anti-H.pylori IgG dete...

Background and purpose: Urticaria is a pruritic cutaneous disease characterized by weal and flare.  Acute and chronic urticaria affects the quality of life. Some abnormalities are associate or comorbid with urticaria. The purpose of this study was to examine comorbid conditions in patients with urticaria.  Materials and Methods: We searched in many databases including Google Scholar, PubMed, S...

Chronic urticaria is a common condition that can be very disabling when severe. A variety of causes has been reported to induce urticaria, including food, infections, drugs and other factors. In more than 50% of cases of chronic urticaria, however, the cause remains unknown and cannot be ascribed to allergic, physical, environmental or other factors. Although an association between chronic idio...

Sir, Chronic idiopathic urticaria may be autoimmune in origin (autoimmune urticaria), caused by functional autoantibodies that activate mast cells and basophils through cross linking the high affinity IgE receptor (FcεRIα) to secrete histamine. An incidence of 30% to 50% has been reported by various investigators. While there are no clinical features that distinguish ordinary urticaria from aut...

The term “chronic idiopathic urticaria” denotes a spectrum of conditions with different poorly understood pathogenetic mechanisms in which the release of histamine plays a role. Nonsedating second-generation H1 antihistamines are postulated to be the first line of treatment of chronic idiopathic urticaria by national and international guidelines, but as control is not always achievable with the...