نتایج جستجو برای: icd

تعداد نتایج: 11896  

زارع میرک آبادی, عباس , شهرام‌یار, زهرا , مروتی, حسن ,

سابقه و هدف: مطالعات قبلی روی ICD-85 (پپتید مشتق از زهر مار و عقرب )که توسط محققین موسسه سرم سازی رازی استخراج شده است، اثر مهاری این ترکیب را در گروه سلول‌های سرطانی پستان (MDA-MB 231) نشان داد. این تحقیق به منظور روشن شدن مکانیسم اثر ICD-85 روی سلولهای سرطانی HL-60 صورت گرفته است. روش بررسی: ابتدا سیتوتوکسیسیته ICD-85 روی سلول HL-60 توسط تست MTT تعیین شد و تغییرات مرفولوژیکی حاصل از ICD-85 ...

ژورنال: Iranian Biomedical Journal 2015
Sarzaeem, Ali, Zare Mirakabadi, Abbas,

Background: Our previous in vivo studies confirmed that ICD-85, as an anticancer agent, was able to prevent further growth of breast tumors and expand the life expectancy of mice with breast cancer. Methods: Blood collection was carried out before, 1, 3, and 6 hours after ICD-85 injection. Sera were used to determinate the cardio and hepatic enzymes levels, including ALT, AST, LDH, CPK, and Ck-...

Journal: :Heart, Vessels and Transplantation 2019

Journal: :Indian Heart Journal 2014

      ICD-85 (venom derived peptides) has anti-proliferative effect and anti-angiogenesis activity on cancer cells. This study was performed to test the effect of ICD-85, on Human breast adenocarcinoma (MCF-7) and normal Human Dermal Fibroblasts (HDF) cell lines. In this experimental study, Mitochondrial activity, Neutral red uptake, Lactate dehydrogenase (cell necrosis), and cell morphology we...

Journal: :the iranian journal of pharmaceutical research 0
abbas zare mirakabadi department of venomous animals and antivenom production, razi vaccine and serum research institute, karaj, iran. zahra shahramyar department of venomous animals and antivenom production, razi vaccine and serum research institute, karaj, iran. hasan morovvati quality control department, razi vaccine and serum research institute, karaj, iran. mohsen lotfi quality control department, razi vaccine and serum research institute, karaj, iran. ali nouri electron microscopy department, razi vaccine and serum research institute, karaj, iran.

our previous studies revealed an inhibitory effect of icd-85 (venom derived peptides) on breast cancer cell line mda-mb231. icd-85 was also confirmed by in-vivo studies to suppress the breast tumor in mice. however, the exact mechanism of icd-85 was unknown. hence, the present study was undertaken to assess the mechanism of icd-85 effect as an anti-proliferative agent of cancer cells. the effec...

Journal: :Bundesgesundheitsblatt - Gesundheitsforschung - Gesundheitsschutz 2018

Journal: :Australian & New Zealand Journal of Psychiatry 2014

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