objective(s): in order to grow cells in a three-dimensional (3d) microenvironment, self-assembling peptides, such as puramatrix, have emerged with potential to mimic the extracellular matrix. the aim of the present study was to investigate the influence of the self-assembling peptide on the morphology, survival, proliferation rate, migration potential, and differentiation of human meningioma st...

ovarian mixed germ cell tumors consisting of endodermal sinus tumor and immature teratoma are very rare and have been reported only in a few case reports. here we report a rare mixed germ cell tumor of ovary which was consisted of endodermal sinus tumor and immature teratoma components with an unusual intraabdominal location. patient was a 21 years old girl with the chief compliant of abdominal...

background: giant cell tumor is a benign but locally aggressive bone neoplasm which uncommonly involves the skull. giant cell tumor (gct) of the sphenoid bone is relatively rare. in this report, we describe a tumor of the greater wing of left sphenoid bone. case presentation: a 31-year-old female was presented with headache, proptosis and diplopia of her left eye. cranial magnetic resonance ima...

systemic amyloidosis and testicular interstitial tumor are rare conditions in birds and this is the first report in iran. a male zebra finch was presented because of white diarrhea, anorexia, loss of weight and lethargy. at necropsy, the small intestine was edematous and congested. the spleen appeared pale. the liver was large, firm and brown. one testis was cystic and neoplastic and the remain...

introduction: granular cell tumors (gcts) are rare and mostly benign soft tissue tumors. though they have been reported in all parts of body, they are generally located in the head and neck region, especially on the tongue. some malign forms exist, but these have been rarely reported. granular cell tumors have a neural origin and, in immunohistochemical evaluations, they express s-100 and neuro...

Several cell surface properties of three B16 melanoma var iant lines, which exhibit differing lung-colonizing capacities, have been examined. Equal numbers of cells from the B16F10Lr and B16-F1 lines, injected i.v. into syngeneic mice, produced significantly fewer lung nodules than did cells of the B16-F10 line. These wide differences in biological behavior could not, however, be ascribed to ma...

Several cell surface properties of three B16 melanoma var iant lines, which exhibit differing lung-colonizing capacities, have been examined. Equal numbers of cells from the B16F10Lr and B16-F1 lines, injected i.v. into syngeneic mice, produced significantly fewer lung nodules than did cells of the B16-F10 line. These wide differences in biological behavior could not, however, be ascribed to ma...

sertoli cell tumors of the testis are extremely rare tumors with a heterogeneous pathology. three histological variants have been described: sertoli cell tumor not otherwise specified (nos), large cell calcifying sertoli cell tumor and the sclerosing sertoli cell tumor. the sclerosing sertoli cell tumor described herein is associated with prominent stromal sclerosis. they present as painless sc...

a case of g iant cell tumor of t he vertebra simulat ing vert ebra plana was reported . t he d i agnos i s o f t he vertebra plana should not be confirmed by t he history of the patient and radiologica l manifestation alone . it can onlybe confirmed by biopsy . bone l esions of the spine i s one of the most di fficul t problems t o diagnosis and t r eat . spinal tumors a r e either primary or m...

background: adipose derived stem cells (ascs) provoke the accumulation and expansion of regulatory t cells, leading to the modulation of immune responses in tumor microenvironment. objective: to assess the effect of tumoral ascs on the trend of regulatory t cells differentiation. methods: peripheral blood naïve cd4+ t cells were co-cultured with ascs derived from breast cancer or normal breast ...