UNLABELLED To develop a (99m)Tc renal tracer with a capacity to measure effective renal plasma flow comparable to that of the clinical gold standard (131)I-o-iodohippurate ((131)I-OIH) and superior to that of (99m)TcO-mercaptoacetyltriglycine, which has a clearance only 50%-60% that of (131)I-OIH, we investigated (99m)Tc-tricarbonyl nitrilotriacetic acid (Na(2)[(99m)Tc(CO)(3)(NTA)]). This radio...

Relation to high absorption fraction of Tc sestamibi by kidneys in heart scan and these organs are near to generation organs (Ovaries and uterus). Urinary system (kidneys and urinary bladder) are specified as sources organs. The main object of this study is to determine the absorbed dose in these critical organs. we have set amount of absorbed fraction radiopharmaceutical in position of kidneys...

Background: Radioiodine therapy has proven to be an effective method in the treatment of patients with differentiated thyroid carcinoma after thyroidectomy. The scope of this study is to describe a method to obtain the dose of organs using medical internal radiation dosimetry (MIRD) method. At the end, the results of MIRD calculations were compared with thermoluminescent dosimeter (TLD...

UNLABELLED In an ongoing effort to develop a renal tracer with pharmacokinetic properties comparable to p-aminohippurate and superior to those of both (99m)Tc-mercaptoacetyltriglycine and (131)I-o-iodohippurate ((131)I-OIH), we evaluated a new renal tricarbonyl radiotracer based on the aspartic-N-monoacetic acid (ASMA) ligand, (99m)Tc(CO)(3)(ASMA). The ASMA ligand features 2 carboxyl groups and...

UNLABELLED In this study we compared whole body scintigraphy with Tc-99m-methoxyisobutylisonitrile (MIBI) and Iodine-131 NA (131I) for detection of residual and/or metastatic disease in well differentiated thyroid carcinoma. METHODS MIBI and I-131 scans were obtained in 60 patients. TSH measurements were done in all the patients prior to scintigraphy. RESULTS Out of 60 patients, for whom bo...

Background: Reliable estimation of radiation-absorbed dose is necessary to evaluate the benefits and the risks of radiopharmaceuticals used for diagnostic or therapeutic purposes in nuclear medicine. Materiel and Methods: This study included 47 patients treated with iodine-131 for Graves’ disease. A comparative study between Geant4 Monte Carlo simulation and MIRD formalism was carried out to ev...

The thyroid uptake at 20 minutes of intravenously administered Technetium-99(m) ((99m)Tc) was measured in 117 patients with a standard scintillation counter. Patients were divided into three groups on the basis of clinical assessment, four-hour (131)I uptake, triiodothyronine (T-3) resin uptake, and protein-bound iodine measurements.In 31 patients with no evidence of thyroid disease the mean (9...

Introduction Dose calculation of tumor and surrounding tissues is essential during prostate brachytherapy. Three radioisotopes, namely, 125 I, 103 Pd, and 131 Cs, are extensively used in this method. In this study, we aimed to calculate the received doses by the prostate and critical organs using the aforementioned radioactive seeds and to investigate the effect of scattering contribution for t...

Boron Neutron Capture Therapy (BNCT) is a relatively safer technology for killing cancer cells, one of which the Glioblastoma multiforme. One main components BNCT equipment collimator functions as an exit point epithermal neutron particles that hit cells. In addition to experimental method, research can be carried out by modeling, including using MCNPX software based on Monte Carlo Method. This...

Introduction: The present study was aimed to assess the diagnostic performance of the two imaging methods of 131I-metaiodobenzylguanidine (131I-MIBG) and 99mTc-hydrazinonicotinyl-Tyr3-Octreotide (99mTc-HYNIC-TOC) in diagnosis and localization of pheochromocytoma and neuroblastoma. Methods: This study ...