نتایج جستجو برای: hypothyroxinemia

تعداد نتایج: 201  

Journal: :Pharmacophore 2021

In normal pregnancy, the maternal thyroid gland undergoes alterations to maintain necessary levels of hormones (THs) in each gestational period. However, various factors may reduce TH levels, potentially impacting onset and development pregnancy. Such cases dysfunction are divided into overt (clinical) hypothyroidism, subclinical or isolated hypothyroxinemia, depending on severity deficiency. T...

Journal: :Pakistan Journal of Medical and Health Sciences 2022

Several questions persist, even though our considerate of the connections concerning thyroid function and pregnancy is growing. It essential to utilize a TSH range for trimester when evaluating during pregnancy. Low levels in initial should be regarded as natural rather than problematic. not exceed 2.5 mIU/L 1st 3.0 2nd 3rd trimesters. The major form treatment prenatal period women with overt h...

2011
Joanna Klubo-Gwiezdzinska Kenneth D. Burman Douglas Van Nostrand Leonard Wartofsky

The prevalence of overt and subclinical hypothyroidism during pregnancy is estimated to be 0.3-0.5% and 2-3%, respectively. Thyroid autoantibodies are found in 5-18% of women in the childbearing age. The aim of this review is to underscore the clinical significance of these findings on the health of both the mother and her offspring. Methods of evaluation of thyroid function tests (TFTs) during...

Journal: :Toxicological sciences : an official journal of the Society of Toxicology 2011
Marta Axelstad Julie Boberg Christine Nellemann Maria Kiersgaard Pernille Rosenskjold Jacobsen Sofie Christiansen Karin Sørig Hougaard Ulla Hass

The widely used fungicide mancozeb has been shown to cause hypothyroxinemia and other adverse effects on the thyroid hormone system in adult experimental animals. In humans, hypothyroxinemia early in pregnancy is associated with adverse effects on the developing nervous system and can lead to impaired cognitive function and motor development in children. The aim of the present study was therefo...

Journal: :Endocrinology 2004
Eva Ausó Rosalía Lavado-Autric Estela Cuevas Francisco Escobar Del Rey Gabriella Morreale De Escobar Pere Berbel

Epidemiological studies and case reports show that even a relatively minor degree of maternal hypothyroxinemia during the first half of gestation is potentially dangerous for optimal fetal neurodevelopment. Our experimental approach was designed to result in a mild and transient period of maternal hypothyroxinemia at the beginning of corticogenesis. Normal rat dams received the goitrogen 2-merc...

Journal: :European journal of endocrinology 2011
Helton Estrela Ramos Melina Morandini Aurore Carré Elodie Tron Corinne Floch Laurent Mandelbrot Nathalie Neri Benoit De Sarcus Albane Simon Jean Paul Bonnefont Jeanne Amiel Isabelle Desguerre Vassili Valayannopoulos Mireille Castanet Michel Polak

CONTEXT Monocarboxylate transporter 8 (MCT8 or SLC16A2) mutations cause X-linked Allan-Herndon-Dudley syndrome. Heterozygous females are usually asymptomatic, but pregnancy may modify thyroid function and MCT8 is expressed in the placenta, suggesting that maternal and fetal abnormalities might develop even in the absence of MCT8 fetal mutation. Genetic counseling is so far based on X-linked tra...

2016
Zhao Tong Zhang Xiaowen Chen Baomin Liu Aihua Zhou Yingying Teng Weiping Shan Zhongyan

The objective of this study was to evaluate the association between maternal subclinical thyroid dysfunction and autoimmunity with the risk for intrauterine growth restriction (IUGR).Design is a systematic review and meta-analysis.A literature search was conducted using PubMed, Embase, and Cochrane database. A combination of 2 key words was used to search for the eligible studies: one indexed t...

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