Objective(s):Hypothermia and decompressive craniectomy (DC) have been shown to be neuroprotective. This study was designed to evaluate neuroprotective effects of delayed singular or combination of DC and local hypothermia on stroke. Materials and Methods: Cerebral ischemia was induced in 48 Wistar rats assigned to 4 groups: control, decompressive craniectomy (DC), local hypothermia (LH), combin...

Background: Asphyxia is a perinatal accident with a high mortality rate, therapeutic hypothermia in both head or whole body was suggested as effective therapeutic methods. In this study, we compare these methods in neonates with asphyxia.Methods and Materials: 16 neonates with asphyxia in two hospitals including Alzahra(head hypothermia) and Taleghani hospital (total body hypothermia) went unde...

Objective(s):The mechanism of hypothermia action of acetaminophen (APAP) remains unclear even 125 years after its synthesis. Acetaminophen produces hypothermia. The mechanism of this reduction in core body temperature is not clear but evidence shows that it is not dependent on opioid and cannabinoid receptors. Because of strong documents about the roles of GABA and benzodiazepine receptors in h...

hypothermia is one of the main causes of neonatal mortality in developing countries. the aim of this prospective study was to determine the relationship between hypothermia at birth and the risk of mortality or morbidity among neonates born in imam hospital in tehran, iran. during a one-year period, body temperature was taken from all newborns using a low-reading rectal thermometer, immediately...

Background: Ondansetron and hypothermia are both known to induce bradycardia or QT interval prolongation, thus placing affected patients at risk of cardiac arrest. Case Report: Herein, we report the case a 97-year-old woman who initially presented with confusion hypothermia, experienced severe asystolic arrest after 4 mg intravenous ondansetron bolus injection. Conclusion: is associated QTc whi...

Abstract The aim of the present study was to establish a novel method for inducing deep hypothermia in rats. Cooling rats anesthetized with isoflurane caused time-dependent decrease rectal temperature, but cardiac arrest occurred before their body temperature reached 20 °C when inhalation continued during cooling process. Stopping 22.5 successfully induced hypothermia, although stopping at 27.5...

abstract background: after the umbilical cord is cut, premature neonates face numerous problems including hypothermia. with regard to serious complications of hypothermia and incapability of conventional methods in preservation of neonates’ temperature after admission, the researcher decided to conduct a study on the effects of two polyethylene covers in prevention of hypothermia among prematur...

background: neonatal deaths mostly occur within the first one week and first 24 hours of life from a variety of conditions. objective: to examine the role of significant hypothermia and hypoglycaemia, in addition to some other factors, in neonatal mortality occurring within the first 24 hours of admission.methods: a prospective study of newborn infants hospitalized within the first 24 hours of ...