Extracellular vesicles (EVs) secreted from adipose-derived stem cells (ADSCs) are known to exhibit collagen synthesis and migration activity in fibroblasts. These EVs can be used as a regenerative medicine for cosmetic medicinal materials. Royal jelly (RJ) is produced the hypopharyngeal mandibular glands of honeybees (nurse bee), which contains apicin 10-hydroxy-2-decenoic acid, compounds that ...

OBJECTIVES/HYPOTHESIS Narrow band imaging combined with magnifying endoscopy (NBI-ME) is useful for the detection of superficial cancer in the oropharynx, hypopharynx, and esophagus. We used NBI-ME to evaluate the frequency of superficial cancer spread (SCS) contiguous with advanced oropharyngeal and hypopharyngeal cancers and esophageal cancers. STUDY DESIGN Retrospective. METHODS We retro...

BACKGROUND Primary laryngeal adenocarcinomas are uncommon and typically of salivary or seromucinous glands origin. Similarly, metastatic adenocarcinoma, including intestinal origin to the larynx, is a rare occurrence. METHODS We present a case of a 63-year-old woman with odynophagia and an epiglottic mass of 2 months' duration. Physical examination revealed a large mass involving the entire e...

Hypopharyngeal hamartomas are quite rare tumors that may cause nutritional or respiratory problems in neonates and infants. They may be confused with other benign laryngeal lesions. In this study a 7-month-old infant with congenital stridor and positional dyspnea caused by a hypopharyngeal hamartoma was reported with review of the literature. Hypopharyngeal hamartomas should be considered in th...

OBJECTIVES/HYPOTHESIS Recent reviews of laryngeal cancer have detected a trend toward reduced survival, linked temporally to an abrupt change in treatment of these patients during the 1990s to nonsurgical regimens. Because organ preservation also is an important goal for hypopharyngeal cancer, we sought to determine treatment trends and survival data for patients with hypopharyngeal squamous ce...

The aim of this study was to explore the relationship between HPV16 infection, p16 protein expression and prognosis in patients with hypopharyngeal carcinoma. Totally 46 cases of hypopharyngeal carcinoma specimens were selected from January 1, 2004 to December 31, 2011 in Tangshan Union Hospital. PCR-reverse dot blot hybridization was used to detect infection of HPV16, and SP immunohistochemica...