نتایج جستجو برای: hypolipidemia

تعداد نتایج: 97  

2003
JANARDAN REDDY MASAHIRO CHIGA

Previous studies (1-3) demonstrated a significant increase in number of microbodies (peroxisomes) and concomitant elevation in catalase activity in male rat liver following administration of ethyl-o, p-chlorophenoxyisobutyrate (clofibrate, CPIB), a hypolipidemic drug that lowers serum cholesterol and triglycerides in man (4) and in experimental animals (5, 6) . Neither the significance of micro...

Journal: :Biosaintifika: Journal of Biology & Biology Education 2020

Journal: :The New England journal of medicine 2010
Kiran Musunuru James P Pirruccello Ron Do Gina M Peloso Candace Guiducci Carrie Sougnez Kiran V Garimella Sheila Fisher Justin Abreu Andrew J Barry Tim Fennell Eric Banks Lauren Ambrogio Kristian Cibulskis Andrew Kernytsky Elena Gonzalez Nicholas Rudzicz James C Engert Mark A DePristo Mark J Daly Jonathan C Cohen Helen H Hobbs David Altshuler Gustav Schonfeld Stacey B Gabriel Pin Yue Sekar Kathiresan

We sequenced all protein-coding regions of the genome (the "exome") in two family members with combined hypolipidemia, marked by extremely low plasma levels of low-density lipoprotein (LDL) cholesterol, high-density lipoprotein (HDL) cholesterol, and triglycerides. These two participants were compound heterozygotes for two distinct nonsense mutations in ANGPTL3 (encoding the angiopoietin-like 3...

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