38 Background: Shorter courses of radiation therapy have advantages for patients and could result in significant cost savings for the healthcare system. The British and Canadian experience with hypo-fractionated regimens have shown that survival rates in appropriately selected patients is equivalent to other methods. However, adoption of these techniques has been hindered by fear of potential c...

The use of improved technology has fostered increasing interest in hypofractionated radiation therapy for prostate cancer. There also is convincing evidence that an unusual aspect of prostate cancer radiobiology allow a different approach to dose escalation that is radiobiological in nature. The aim of this paper is to explain the rationale behind hypo fractionated high -dose intensity -modulat...

Background: Three-dimensional conformal radiotherapy is a new tool in the Senegalese therapeutic arsenal. Symptomatic bone metastases affect quality of life patients. Analgesic proposed to patients relieve them. Patients and methods: A prospective descriptive study was carried out on all with symptomatic metastasis. Hypo-fractionated performed painful site. The visual analogue scale used assess...

Thoracic radiotherapy causes damage of normal lung tissue, which limits the cumulative radiation dose and, hence, confines the anticancer efficacy of radiotherapy and impacts the quality of life of tumor patients. Ras-homologous (Rho) small GTPases regulate multiple stress responses and cell death. Therefore, we investigated whether pharmacological targeting of Rho signaling by the HMG-CoA-redu...

BACKGROUND The locally advanced head and neck cancer with fixed nodes are incurable and has a short survival. This study aims to evaluate the symptom relief, disease response and acute toxicity after palliative hypo-fractionated radiotherapy. METHODS Between December 2010 to June 2011, previously untreated 50 patients who had histopathologically proved of head and neck squamous cell carcinoma...