RP-HPLC chromatographic method was developed for determination of Hyoscine Butyl Bromide (HBB) and Dipyrone ( DIP). In this method, HBB and DIP were separated by using C18 (25 cm×4.6 mm i.d. 5μm particle size) column as a stationary phase and using water: methanol (50:50) v/v pH adjusted to 7.0 with triflouroacetic acid and triethylamine) as a mobile phase, maintaining the flow rate at 1.0 mL m...

Current techniques used to investigate the mechanisms responsible for the sensory responses to distension of the human esophagus provide limited information because the degree of circumferential stretch required to determine tension can only be inferred. We used impedance planimetry to measure the cross-sectional area during esophageal distension to ascertain the degree of stretch and tension t...

A sixty-seven year old male patient admitted to the emergency department with complaints of epigastric pain and dark colored vomit which occurred while eating. The pain had a colic-like characteristic and spread to the chest. The patient vomited only once and continued to retch. No comorbid disease was present. The patient's blood pressurewas 167/101mmHg, pulsewas 67/min, respiratory rate was 2...

cis-polybutadiene was functionalized using in–situ generated dmd as oxidant and tetra-n-butyl ammonium bromide as phase transfer catalyst (ptc). the epoxidation process was investigated by 1hnmr spectroscopy. 1hnmr spectrum analysis of products confirms the absence of ring opening side products in epoxidation reaction. various factors such as reaction temperature, reaction time and the concentr...