many aldehydes are important components of natural flavours. they are used in food, cosmetic, and biomedical industries in large amounts. plant cells or microorganisms carry out their production by biotransformation, which is one of the biotechnological methods that allow them to be defined as 'natural'. cell cultures of silybum marianum and peganum harmala have been studied with a vi...

A total of eleven alkali-released, aromatic compounds were identified by HPLC, MS and NMR analyses in cell wall extracts from Arabidopsis thaliana roots. Nine of them together constituted the three complete series of 4-hydroxy-, 4-hydroxy-3-methoxy, and 4-hydroxy-3,5-dimethoxy-substituted benzaldehydes, benzoic acids and cinnamic acids. The other two were indolic metabolites: indole-3-carboxyli...

A ruthenium complex formed from commercially available [Ru(p-cymene)Cl2]2 and 1,4-bis(diphenylphosphino)butane catalyzes the racemization of aromatic α-hydroxy ketones very efficiently at room temperature. The racemization is fully compatible with a kinetic resolution catalyzed by a lipase from Pseudomonas stutzeri. This is the first example of dynamic kinetic resolution of α-hydroxy ketones at...

Treatment of various aliphatic and aromatic aldoximes with the hypervalent iodine(iii) reagents (diacetoxyiodo)benzene (DIB) or Koser's reagent [hydroxy(tosyloxy)iodo]benzene (HTIB) gave, respectively, N-acetoxy or N-hydroxy amides in good yields rather than the expected nitrile oxide dimerised product oxadiazole-N-oxides reported to be formed with other oxidising and hypervalent iodine reagent...

The carcinogenicity of seven metabolites of the essential amino acid tryptophan and nine other nitrogen-containing aromatic compounds was studied by the individ ual suspension of these chemicals in cholesterol pellets and the surgical implantation of the pellets into the bladders of mice. Pellets consisting of the 8-methyl ether of xanthurenic acid, xanthurenic acid, 8-hydroxyquinaldic acid, 3-...

gens in the neoplastic processes induced by these compounds. The fact that the aromatic aminoazo dyes are carcinogenic primarily in the liver and generally not at sites of local application (16) has suggested that the aminoazo dyes are likewise active through the formation of reactive metabolites. The structural similarity be tween the aminoazo dyes and the carcinogenic aromatic amines and amid...

gens in the neoplastic processes induced by these compounds. The fact that the aromatic aminoazo dyes are carcinogenic primarily in the liver and generally not at sites of local application (16) has suggested that the aminoazo dyes are likewise active through the formation of reactive metabolites. The structural similarity be tween the aminoazo dyes and the carcinogenic aromatic amines and amid...

The aromatic polyketones 3a-d are versatile compounds for the synthesis of the multi-1,2,3-selenadiazole aromatic derivatives 1a-d. The preparation starts with the reaction between the multi-bromomethylene benzene derivatives 2a-d and 4-hydroxy- acetophenone to give compounds 3a-d which are transformed through the reaction with semicarbazide hydrochloride or ethyl hydrazine carboxylate into the...

Under secondary metabolic conditions, the white-rot basidiomycete Phanerochaete chrysosporium degraded 2,7-dichlorodibenzo-p-dioxin (I). The pathway for the degradation of I was elucidated by the characterization of fungal metabolites and oxidation products generated by lignin peroxidase (LiP), manganese peroxidase (MnP), and crude intracellular cell-free extracts. The multistep pathway involve...