BACKGROUND Differential diagnosis of hydatidiform moles from non-molar specimens as well as their sub-classification such as complete and partial hydatidiform moles are important for clinical management and accurate risk assessment for persistent gestational trophoblastic disease, but diagnosis based solely on histomorphology suffers from poor interobserver and intraobserver reproducibility. ...

Wijngaard, Jeroen P. H. M. van den, Asli Umur, Raymond T. Krediet, Michael G. Ross, and Martin J. C. van Gemert. Modeling a hydropic recipient twin in twin-twin transfusion syndrome. Am J Physiol Regul Integr Comp Physiol 288: R799–R814, 2005. First published November 11, 2004; doi:10.1152/ajpregu.00635.2004.— We developed a mathematical model of twin-twin transfusion syndrome (TTTS) that inclu...

Context Long-standing diabetes mellitus results in autonomic nervous system dysfunction, leading to gastroparesis and cholecystoparesis. The latter can result in hydropic gallbladder, a condition that arises from the accumulation of mucinous secretions within the gallbladder, usually caused by obstruction of the cystic duct, but not in the case of the patients with diabetes that we have illustr...

We developed a mathematical model of twin-twin transfusion syndrome (TTTS) that includes a hydropic recipient twin, adding interstitial and intracellular fluid compartments, fetal congestive cardiac failure, and the dynamics of renin-angiotensin system (RAS) mediators to our previous TTTS model. Ten differential equations for each twin, coupled by the net fetofetal transfusion of blood and bloo...

AIM To determine the potential value of interphase cytogenetic and argyrophilic nucleolar organiser region (AgNOR) analyses in the diagnosis and classification of hydatidiform moles. METHODS Serial tissue sections from 37 hydatidiform moles, histologically classified as 11 complete and 15 partial, and from 11 hydropic abortuses were examined by in situ hybridisation using digoxigenin labelled...

Masaharu Fukunaga, M.D. Department of Pathology, the Jikei University Daisan Hospital, Tokyo, Japan Hydatidiform moles With the increased use of ultrasound hydatidiform mole (HM) is being diagnosed at increasingly early stages of gestation. As villous edema is not fully developed, we cannot make a diagnosis of HM by macroscopic observation. Furthermore, microscopically the classic features of c...

OBJECTIVE To review the diagnosis, treatment, and outcome of fetal atrial flutter compared with supraventricular tachycardia. DESIGN Retrospective review of published reports: 11 papers about fetal tachyarrhythmia published between 1991 and 2002 were selected for review. MAIN OUTCOME MEASURES All selected studies were analysed for the type of arrhythmia, degree of atrioventricular block in ...

Fetal supraventricular tachycardia (SVT) can be successfully treated transplacentally, but in cases where fetal hydrops develops there is considerable morbidity and mortality. The present study was carried out to establish whether the introduction of flecainide altered obstetric management and fetal outcome. A retrospective analysis took place of 51 singleton pregnancies which were referred to ...