Evidence in support of safety of a gene delivery procedure is essential toward gene therapy. Previous studies using the hydrodynamics-based procedure primarily focus on gene delivery efficiency or gene function analysis in mice. The current study focuses on an assessment of the safety of computer-controlled and liver-targeted hydrodynamic gene delivery in dogs as the first step toward hydrodyna...

We present a family of equations of state within a quasiparticle model adjusted to lattice QCD and study the impact on azimuthal flow anisotropies and transverse momentum spectra within hydrodynamic simulations for heavyion collisions at energies relevant for LHC.

Some principal value integrals of Glauert’s type are calculated analytically. These integrals appear when dealing with the hydrodynamic impact problem of a two-dimensional wedge onto a liquid free surface in the potential theory. © 2004 Elsevier Ltd. All rights reserved.

We explore the impact of thermal fluctuations on nanofluidic transport. We develop a generic description of the stochastic motion of a fluid confined in a nanopore, on the basis of the fluctuating hydrodynamics framework. The center of mass of the confined fluid is shown to perform a non-markovian random walk, whose diffusion coefficient depends on the nanopore geometrical characteristics and b...

Recent multidimensional hydrodynamic simulations have demonstrated the importance of hydrodynamic motions in the convective boundary and radiative regions of stars to transport of energy, momentum, and composition. The impact of these processes increases with stellar mass. Stellar models which approximate this physics have been tested on several classes of observational problems. In this paper ...

We present a numerical investigation of the Brownian motion and diffusion of a dumbbell in a two-dimensional periodic potential. Its dynamics is described by a Langevin model including the hydrodynamic interaction. With increasing values of the amplitude of the potential we find along the modulated spatial directions a reduction of the diffusion constant and of the impact of the hydrodynamic in...

The development of a distributed parameter model of microalgae growth is presented. Two modelling frameworks for photo-bioreactor modelling, Eulerian and Lagrangian, are discussed and the complications residing in the multi-scale nature of transport and reaction phenomena are clarified. It is shown why is the mechanistic two time-scale model of photosynthetic factory the adequate model for biot...

There is an increasing demand for knowledge about hydrodynamic, morphological and water quality processes within the estuarine waterways of the Gold Coast. This study describes the development of a suite of hydrodynamic, sediment transport and water quality models for the Gold Coast tidal waterways. The modeling framework described was developed to provide a strategic understanding of waterway ...

Syntactic foams are particulate composite materials that are extensively integrated in naval and aerospace structures as core materials for sandwich panels. While several studies have demonstrated the potential of syntactic foams as energy absorbing materials in impact tests, our understanding of their response to water impact remains elusive. In this work, we attempt a first characterization o...