نتایج جستجو برای: human immune
تعداد نتایج: 1841585 فیلتر نتایج به سال:
Background: During pregnancy, the maternal immune system is in close contact with cells and tissue from the semiallogenic fetus .The human leucocyte antigen (HLA) class Ib molecules, HLA-E, -F and -G, are expressed at the materno-fetal interface. Because of the apparent immunoregulatory functions of these proteins, they may be involved in successful acceptance of the semi-allogenic fetus during...
Background: Programmed cell death protein-1 (PD-1)/PD-L1 pathway is one of the immune checkpoint pathways involved in regulation of the immune responses and suppression of anti-tumor defense. PD-1/B7-H1-blocking antibodies improve immune responses such as cytotoxic activity of CD8+/CD4+T cells and also increase mortality of tumor cells; however their use is accompanied by adverse effects in pat...
human t lymphotropic virus type i (htlv-i) is a retrovirus which is associated with adult t cells leukaemia (atl) and htlv-i-associated myelopathy/tropical spastic paraparesis (ham/tsp) in a minority of htlv-i-infected individuals. it is not clear why a minority of htlv-i-infected individuals develop ham/tsp and majority remains lifelong carriers. it seems that the interaction between the virus...
Human T lymphotropic virus type I (HTLV-I) is a retrovirus which is associated with adult T cells leukaemia (ATL) and HTLV-I-associated myelopathy/tropical spastic paraparesis (HAM/TSP) in a minority of HTLV-I-infected individuals. It is not clear why a minority of HTLV-I-infected individuals develop HAM/TSP and majority remains lifelong carriers. It seems that the interaction between the v...
Respiratory tract infections are the primary cause of morbidity and mortality globally. Human bocavirus 1 (HBoV1), a member Parvoviridae family causes wide spectrum respiratory diseases in children, gastroenteritis adults. The mechanisms latency, persistence, reinfection Bocavirus poorly understood at present due to lack permissive cell lines efficient animal models. Moreover, dual HBoV other v...
Non-responsiveness or poor responsiveness to vaccines are challenging issues in vaccine development, and efforts have been made to find out the potential reasons for these conditions. Intestinal microbiome plays a key role in regulating and development of immune system and the composition and diversity of microbiota in different individuals on the one hand, and the imbalance of intestinal micro...
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