introduction: growth, proliferation, survival, and differentiation are the prominent characteristics of cells, which are affected by cancer. epidermal growth factor receptor (egfr) plays a pivotal role in the effective control of these features. given the significance of egfr signaling pathway in non-small cell lung cancer (nsclc), egfr expression is influential on these cell characteristics. i...

background and aims. many oral squamous cell carcinomas develop from potentially malignant disorders (pmds) which include a variety of lesions and conditions characterized by an increased risk for malignant transformation. this study evaluated the quantitative expression of egfr in normal oral mucosa, oral leukoplakia and oral submucous fibrosis to predict the malignant risk in compliance with ...

      EGFR is a key molecule in cancer cells. EGFR signaling was shown to promote tumor cell proliferation and survival, invasion and angiogenesis and mediate resistance to treatment, including ionizing radiation in preclinical models. We extracted proteins from astrocytoma (III and IV) oligodendroglioma(IV) tumors and normal brain tissues and then evaluated the protein purity by Bradford test ...