نتایج جستجو برای: human embryonic stem cell
تعداد نتایج: 3050379 فیلتر نتایج به سال:
objective(s): sertoli cells support in vivo germ cell production; but, its exact mechanism has not been well understood. the present study was designed to analyze the effect of sertoli cells in differentiation of mouse embryonic stem cells (mescs) to germ cells. materials and methods: a fusion construct composed of a stra8 gene promoter and the coding region of enhanced green fluorescence pro...
objective: pulp and periodontal tissues are well-known sources of mesenchymal stem cells (mscs) that provide a promising place in tissue engineering and regenerative medicine. the molecular mechanisms underlying commitment and differentiation of dental stem cells that originate from different dental tissues are not fully understood. in this study, we have compared the expression levels of pluri...
the stem cells can be considered as the miracle of creation, because, they are a major reservoir of the bioactive factors, molecules and cells. these reservoir cells play a major role in development and growth of the tissues and organs. regardless of the differences in differentiation capacity of embryonic and adult stem cells, both the cells are rich sources of stem cells with therapeutic appl...
Regenerative capacity of mammals is limited and can rarely regenerate a specific organ or tissue fully. Due to these limitations, regenerative medicine seeks efficient and safe cell sources for regeneration of damaged tissues and organs or treatment for incurable diseases. Human embryonic stem cells (HESCs) hold two important properties called self renewal and pluripotency. However, the use of ...
Induced pluripotent stem cells (iPSCs) are reprogrammed from somatic cells through numerous transcription factors. Human induced pluripotent stem cell approaches are developing as a hopeful strategy to improve our knowledge of genetic association studies and the underlying molecular mechanisms. Rapid progression in stem cell therapy and cell reprogramming provides compelling reasons for its fe...
Successful isolation, derivation and culturing of human pluripotent stem cells, including human embryonic stem cells (hESCs) and human induced pluripotent stem (hiPSCs) cells in laboratory scale has opened new horizones for cell therapy applications such as tissue engineering and regenerative medicine. However, most of the cell therapy protocols using these unique cells require large number of ...
Background and Aim: Embryonic stem cells are identified with two unique characteristics. First, they can be maintained and expanded as pure populations of undifferentiated cells, a characteristic which is known as self renewal aspect of embryonic stem cells. Second, these cells can give rise to all body cell types. In the current study, we used a feeder-free condition to differentiate mouse emb...
background: the failure of regeneration after spinal cord injury (sci) has been attributed to axonal demyelination and neuronal death. cellular replacement and white matter regeneration are both necessary for sci repair. in this study, we evaluated the co-transplantation of olfactory ensheathing cells (oec) and embryonic stem (es) cell-derived motor neurons (esmn) on contused sci. methods: oec ...
introduction: considering the importance of co-culture in differentiation of embryonic stem cells, the aim of this study was evaluation of the effect of co-culturing fetal liver stroma cells with p19 cells on the line of differentiation. materials and methods: for this purpose, p19 cells were cultured directly in semisolid medium. these cells proliferated and primarily differentiated to colonie...
regenerative capacity of mammals is limited and can rarely regenerate a specific organ or tissue fully. due to these limitations, regenerative medicine seeks efficient and safe cell sources for regeneration of damaged tissues and organs or treatment for incurable diseases. human embryonic stem cells (hescs) hold two important properties called self renewal and pluripotency. however, the use of ...
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