نتایج جستجو برای: human dermal fibroblast cells
تعداد نتایج: 2644616 فیلتر نتایج به سال:
Wound healing plays an important role in protecting the human body from external infection. Cell migration and proliferation of keratinocytes and dermal fibroblasts are essential for proper wound healing. Recently, several studies have demonstrated that secondary compounds produced in plants could affect skin cells migration and proliferation. In this study, we identified a novel compound DK223...
BACKGROUND Adipose-derived stem cells (ASCs) are mesenchymal stem cells that have recently been applied to tissue repair and regeneration. Keratinocytes and dermal fibroblasts play key roles in cutaneous wound healing. OBJECTIVE We investigated the paracrine effects of ASCs on HaCaT cells (i.e., immortalized human keratinocytes) and human dermal fibroblasts to explore the mechanism of the eff...
Fibroblasts play a pivotal role in the process of cutaneous wound repair, whereas their migratory ability under diabetic conditions is markedly reduced. In this study, we investigated the effect of basic fibroblast growth factor (bFGF) on human dermal fibroblast migration in a high-glucose environment. bFGF significantly increased dermal fibroblast migration by increasing the percentage of fibr...
Achillea eriophora D.C. (Asteraceae), an endemic species in Iran, is used extensively in Iranian folk medicine to treat various ailments, including gastrointestinal disorders, skin inflammations and wound healing. The present study was aimed to investigate the effects of the methanolic extract of A. eriophora leaves on the stimulation of human fibroblast cell proliferation and migration as two ...
Background and purpose: Some skin injuries are caused by occupational skin exposures that are resulted from production of reactive oxygen species and oxidative stress (ROS). Thus, protecting the skin is a key issue. Recently, several surveys have introduced novel alternatives such as nanofibers for skin protection. In this research, Poly (ε-caprolactone) (PCL)/gelatin (Gt)/ Vitamin E (VE) was i...
The Rockefeller University Press $30.00 J. Cell Biol. Vol. 207 No. 2 283–297 www.jcb.org/cgi/doi/10.1083/jcb.201402006 JCB 283 Correspondence to Boris Hinz: [email protected] Abbreviations used in this paper: -SMA, -smooth muscle actin; ANOVA, analysis of variance; DOC, desoxycholate; ES, embryonic stem; FN, fibronectin; hDf, human dermal fibroblast; hDMf, human dermal myofibroblast; LAP...
Dengus, a mosquito-transmitted viral infection, is estimated to cause disease burden of 400 million people worldwide per year. This study was designed elucidate the immunopathogensis initial infection stage by infecting human dermal fibroblasts WS1 cells with DENV-1 and DENV-2. The results showed several discrepancies, which included stronger innate inflammatory response cell death in DENV-2 in...
Tissue engineering applies principles of biology and engineering to the development of functional substitutes for damaged or lost tissues. Tools for the neo-generation of tissue in tissue engineering research include cells, biomaterials and soluble factors. One main obstacle in tissue engineering is the limited availability of autologous tissue specific progenitor cells. This has led to interes...
purpose a metabolic abnormality such as obesity is a major obstacle in the maintenance of the human health system and causes various chronic diseases including type 2 diabetes, hypertension, cardiovascular diseases, as well as various cancers. this study was designed to summarize the recent scientific knowledge regarding the anti-obesity role of curcumin (diferuloylmethane), which is isolated f...
Human fibroblast?derived extracellular vesicles promote hair growth in cultured human hair follicles
Hair loss is a prevalent medical condition affecting both genders. In this study, we investigate the effects of specific class extracellular vesicles (EVs), namely human normal fibroblast-derived EVs (hFB-EVs), on dermal papilla (DP) and outer root sheath (ORS) cells examine molecular mechanisms responsible for hair growth in follicles (HFs). We find that Wnt3a, which maintains hair-generating ...
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