نتایج جستجو برای: htp

تعداد نتایج: 626  

2004
Debasis Sengupta Sandip Mazumder Samuel Lowry

Hydrogen peroxide (H2O2) is a strong oxidizing agent. High concentration H2O2 or High Test Peroxide (HTP) has been used extensively in the past in propulsion applications as mono and bipropellant. At low temperature, HTP can be catalytically decomposed to water and oxygen. Drawbacks to this approach include catalyst poisoning due to the presence of stabilizers in HTP, and susceptibility of the ...

Journal: :The Biochemical journal 2006
Kamel El Omari Annelies Bronckaers Sandra Liekens Maria-Jésus Pérez-Pérez Jan Balzarini David K Stammers

HTP (human thymidine phosphorylase), also known as PD-ECGF (platelet-derived endothelial cell growth factor) or gliostatin, has an important role in nucleoside metabolism. HTP is implicated in angiogenesis and apoptosis and therefore is a prime target for drug design, including antitumour therapies. An HTP structure in a closed conformation complexed with an inhibitor has previously been solved...

2017
Berit Aydin-Schmidt Ulrika Morris Xavier C Ding Irina Jovel Mwinyi I Msellem Daniel Bergman Atiqul Islam Abdullah S Ali Spencer Polley Iveth J Gonzalez Andreas Mårtensson Anders Björkman

BACKGROUND New field applicable diagnostic tools are needed for highly sensitive detection of residual malaria infections in pre-elimination settings. Field performance of a high throughput DNA extraction system for loop mediated isothermal amplification (HTP-LAMP) was therefore evaluated for detecting malaria parasites among asymptomatic individuals in Zanzibar. METHODS HTP-LAMP performance ...

Journal: :Molecules and cells 2007
Jae-Yong Park Eun Mi Hwang Nammi Park Eunju Kim Dong-Gyu Kim Dawon Kang Jaehee Han Wan Sung Choi Pan-Dong Ryu Seong-Geun Hong

There is an increasing demand for high throughput (HTP) methods for gene analysis on a genome-wide scale. However, the current repertoire of HTP detection methodologies allows only a limited range of cellular phenotypes to be studied. We have constructed two HTP-optimized expression vectors generated from the red fluorescent reporter protein (RFP) gene. These vectors produce RFP-tagged target p...

Journal: :American journal of physiology. Regulatory, integrative and comparative physiology 2005
Luca Imeri Susanna Bianchi Mark R Opp

Serotonin is involved in many physiological processes, including the regulation of sleep and body temperature. Administration into rats of low doses (25, 50 mg/kg) of the 5-HT precursor l-5-hydroxytryptophan (5-HTP) at the beginning of the dark period of the 12:12-h light-dark cycle initially increases wakefulness. Higher doses (75, 100 mg/kg) increase nonrapid eye movement (NREM) sleep. The in...

Journal: :Hypertension 2007
Sofía P Salas Andrea Giacaman William Romero Patricio Downey Eduardo Aranda Diego Mezzano Carlos P Vío

Pregnant women with preeclampsia have increased serotonin levels, suggesting a possible role of this amine in abnormal pregnancy. With the hypothesis that an increase in serotonin would reduce volume expansion and cause fetal growth restriction, we evaluated the maternal and fetal effects of the administration of the serotonin precursor 5-hidroxytryptophan (5-HTP) to Sprague-Dawley rats. At pre...

Journal: :Pharmacology & therapeutics 2006
Erick H Turner Jennifer M Loftis Aaron D Blackwell

This paper reviews the preclinical and clinical evidence regarding the use of the dietary supplement 5-hydroxytryptophan (5-HTP) for the treatment of depression. In the absence of supplementation with exogenous 5-HTP, the amount of endogenous 5-HTP available for serotonin synthesis depends on the availability of tryptophan and on the activity of various enzymes, especially tryptophan hydroxylas...

2005
Jürgen Dix Sarit Kraus V. S. Subrahmanian

To date, there has been no work on temporal probabilistic agent reasoning on top of heterogeneous legacy databases and software modules. We will define the concept of a heterogeneous temporal probabilistic (HTP) agent. Such agents can be built on top of existing databases, data structures, and software code bases without explicitly accessing the internal code of those systems and can take actio...

2016
Russell Miller

For a ring R, Hilbert’s Tenth Problem HTP(R) is the set of polynomial equations over R, in several variables, with solutions in R. We consider computability of this set for subrings R of the rationals. Applying Baire category theory to these subrings, which naturally form a topological space, relates their sets HTP(R) to the set HTP(Q), whose decidability remains an open question. The main resu...

Journal: :Endocrinologia japonica 1976
S Ohgo Y Kato K Chihara H Imura K Maeda

Intravenous injections of varying doses of 5-HTP (1, 3 and 5 mg/100 g body wt), a precursor of serotonin, caused a significant and dose-related increase in plasma prolactin concentrations in urethane-anesthetized rats. Increases in plasma prolactin concentrations caused by 5-HTP (1 mg/100 g body wt iv) were abolished by the concomitant administration of L-DOPA (2 mg/100 g body wt iv). Plasma pr...

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