ObjectiveTo evaluate a rabbit model of mandibular box-shaped defects created through an intraoral approach and determine the minimum size defect that would not spontaneously heal during rabbit's natural life (or critical-sized defect, CSD).MethodsForty-five 6-month-old rabbits were randomly divided into five groups (nine each). Mandibular different sizes (4, 5, 6, 8, 10 mm) in each hemimandible...

Hylonome dimensional relationships change little 2,3. Concomitant with the increase in bone size, the internal structure is modified. The average thickness of trabeculae in the proximal femoral metaphysis increases by about a third during the second half of gestation 4. Cortical thickness at the femoral midshaft approximately doubles during the same period 2. Histomorphometric studies of rib an...

OBJECTIVE To investigate in detail the mechanical and structural characteristics of cancellous bone from the femoral distal epiphysis of normal and ovariectomized rats, and to provide reference values in order to improve experimental research on osteoporosis by characterising an alternative and complementary anatomic site. METHODS 40 female Sprague-Dawley rats (10 months old) were randomly di...

BACKGROUND Abnormal longitudinal growth has been identified in the early pubertal stage of idiopathic scoliosis (IS) and is thought to contribute to the development of scoliosis. This phenotype may be caused by abnormal endochondral ossification, but histological evidence is lacking. The aim of this study was to investigate whether there is abnormal endochondral ossification in IS patients at e...

Purpose: Computerized histomorphometric analyses have been widely used as a diagnostic tool for the differential diagnosis of various tumors including breast carcinoma, well grading malignant and evaluation prognosis therapeutic response. The aim present study is to determine association between nuclear morphometric variables clinicopathologic prognostic parameters ER, PR, Cerb-B2 expressions i...

objective(s): the adverse effects of pyridaben on reproductive system in male animals are not well established. this study was designed to elucidate how pyridaben can effects the histomorphometric, hormonal alternations and reproductive functions of balb/c mice .   materials and methods : for this study, 80 adult and apparently healthy male balb/c mice were divided into three groups viz, contro...

OBJECTIVE The goal of this clinical study was to evaluate dental implant survival rates using the concept of a nonfunctional, immediate loading protocol with nonsplinted dental implants in the grafted maxillary sinus during a 52-week period. Random histomorphological and histomorphometric analysis was completed to evaluate the early healing effect of platelet rich plasma (PRP) and 50% autogenou...

PURPOSE To evaluate the effect of platelet-rich plasma (PRP) on autogenous bone graft remodeling during sinus augmentation in a rabbit model. MATERIALS Twelve New Zealand White rabbits were divided randomly into 3 groups based on their time of sacrifice (2, 4, and 8 weeks). All animals underwent a general anesthetic and harvesting of an autogenous bone graft from the right iliac crest with su...