Summa ry The growth of our knowledge of normal and pathological histology has been accelerated by two periods of spectacular technical developments. The first, a t the end of the nineteenth century, produced most of the dye staining methods for sections that are now in use. The second, dating from the 1950's to the present time, has seen the application of electron microscopy, histochemistry an...

Objective(s): The aim of the present research is to investigate the efficacy of L-carnitine (LC) as a complementary therapy to diclofenac sodium (Dic) treatment in a mono-iodoacetate (MIA) induced knee osteoarthritis (OA) rat model, with respect to pain relief and the underlying pathology.Materials and Methods: Fifty adult male albino ra...

The aim of this study was to evaluate CD44v6 protein expression and its prognostic value of CD44v6 in ovarian carcinoma. The expression of CD44v6 was analyzed in 62 patients with ovarian carcinoma by immunohistochemical method. The data obtained were analyzed by univariate and multivariate analyses. The present study clearly demonstrates that tumor tissues from 41 (66.1%) patients showed positi...

Objective(s): Depression during pregnancy negatively affects fetal development. Fluoxetine as a selective serotonin reuptake inhibitor (SSRIs) is used for treatment of gestational depression. This study is trying to determine the effects of fluoxetine on the renal, heart and lung development.Materials and Methods: Fifteen pregnant rats were treated with fluoxetine at 7 mg/kg from days 0 to 21 o...

background: esophageal cancer is the sixth cause of death in the world, there was a lack of population‑based information on the trend and incidence rate of esophagus cancer, so this study aimed to determine the incidence and pathological changes of esophagus cancer in iran. methods: in this study, data were extracted from annual cancer registry reports of iranian ministry of health between 2003...

Objective Adenoid cystic carcinoma (ACC) is a rare malignant tumor originating from the salivary glands. It’s rather bland histological appearance that masks its ultimate biological aggressiveness. Evaluation of cell cycle and mitoses have been useful in predicting malignancy in many tumors. Ki-67 antigen is a human nuclear antigen that presents during all active phases of cell cycle. The aim ...

objective adenoid cystic carcinoma (acc) is a rare malignant tumor originating from the salivary glands. it’s rather bland histological appearance that masks its ultimate biological aggressiveness. evaluation of cell cycle and mitoses have been useful in predicting malignancy in many tumors. ki-67 antigen is a human nuclear antigen that presents during all active phases of cell cycle. the aim o...

diabetes mellitus is the most common cause of chronic renal disorders and end-stage kidney disease in developed countries. it is the major cause of dialysis and transplantation. failure in renal function causes wide disorders in the body. diabetes results in wide range of alterations in the renal tissue. it is believed that early histological changes in diabetic nephropathy are detectable 2 yea...