Kikuchi-Fujimoto’s disease (KFD), histologically described as necrotising histiocytic lymphadenitis, is a benign self-limiting disease though a few fatalities have been reported. It is uncommon outside Japan and other Asiatic countries and thus lack of awareness among physicians may have led to its underdiagnosis or misdiagnosis as lymphoma or tuberculosis. It has recently gained importance due...

Kikuchi-Fujimoto disease is a rare benign condition of necrotising histiocytic lymphadenitis with unknown aetiology. We describe here a 30-year-old African American female who presented with fever, generalized rash, cervical lymphadenopathy, and oral candidiasis and was found to have Kikuchi-Fujimoto disease on lymph node biopsy with low CD4 count. The initial presentation was concerning for ac...

OBJECTIVE To evaluate the role of fine-needle aspiration cytology in the diagnosis of human immunodeficiency virus (HIV)-associated lymphadenopathy. DESIGN Case series. SETTING Tertiary care teaching hospital, India. PATIENTS Fifty consecutive HIV-positive patients, who presented with lymphadenopathy at the out-patient department and antiretroviral therapy clinic. RESULTS Tubercular lym...

kikuchi-fujimoto disease or histiocytic necrotizing lymphadenitis is an idiopathic, self-limiting disorder and predominantly affects young women. we report a 35-year-old female who presented with soft to firm cervical lymphadenopathy and neck pain. she had multiple enlarged cervical nodes. examination of other systems was normal. lymph node biopsy was performed, and the histological features, a...

Kikuchi disease, also called histocytic necrotizing lymphadenitis or focal histiocytic lymphadenitis, is a rare, idiopathic and generally self limited cause of lymphadenitis. It was first described in 1972 in Japan. The most common clinical manifestation is cervical lymphadenopathy with or without systemic symptoms & signs. It almost always runs a benign course and resolves in several weeks to ...

Eleven cases of histiocytic necrotizing lymphadenitis were studied. Originally four were misdiagnosed as cervical tuberculous lymphadenitis. The characteristic symptoms and signs were local tenderness, fever, leucocytopenia and good prognosis. Antibody to Epstein-Barr virus was elevated in 2 of 3 cases. Biopsy of the affected lymph node was necessary when the differential diagnosis from lymph n...

hyperimmune reaction to We stained our material using the an unknown aetiological agent such as a napthol-ASD-chloroacetate method, but virus. were unable to identify any convincingly Our use of the "unqualified term necropositive cells or debris. Feller et al' also used tizing lymphadenitis" was criticised by Dr this technique but do not mention any posiJM Woodruff of the Memorial Sloantive fi...

Kikuchi-Fujimoto disease (KFD) is a benign, self-limiting disease characterized by histiocytic necrotising lymphadenitis. Though several viral agents or an autoimmune etiology has been proposed as causative, the exact cause remains unknown. It has a female predilection and most commonly seen among young Asian people. Patients usually present with a febrile illness and the presence of lymphadeno...

Case. 38-year-old lady was referred to the ENT clinic with history of right-sided facial pain, otalgia, and odynophagia. Clinical examination revealed enlarged right-sided lymph nodes in the neck. Further radiological scans showed a mass near the carotid and enlarged level V lymph nodes. Lymphoma was initially suspected. Fine-needle aspiration and excision biopsy were undertaken. Histological a...

INTRODUCTION Kikuchi's disease is a benign form of cervical lymphadenopathy that commonly affects young adults. We report a case series from our hospital. METHODS The clinical features of 23 cases of Kikuchi's disease diagnosed at Changi General Hospital over a seven year period are presented. The cases were identified from pathology records using the search term histiocytic necrotising lymph...