Results: Results demonstrated that OC treatment or nicotine exposure led to increased hemorheological (blood viscosity, hematocrit and plasma viscosity), prothrombotic (plasminogen activator inhibitor-1), proinfl ammatory (Creactive protein, uric acid, neutrophil/lymphocyte ratio and platelet/lymphocyte ratio) and anti-infl ammatory (corticosterone) markers. However, these effects except that o...

Background: The purpose of this study was to determine the relationship between early onset sepsis and increased levels of Creactive protein (CRP) and interleukin-6 (IL-6) in cord plasma. Methods: A prospective study was conducted in 141 premature infants delivered with gestational ages of 26-35 weeks. IL-6 and CPR were measured by enzyme-linked immunoassay in the cord plasma of the neonates. A...

Background: Chronic low-grade systemic inflammation presented in Type 2 diabetes mellitus plays a major role in disease progression as well as development of micro- and macro-vascular complications of diabetes. Therefore, reducing inflammation can be beneficial in prevention of diabetes complications. Objectives: To investigate the association between insulin resistance and inflammatory markers...

Background Juvenile Arthritis Disease Activity Score (JADAS) is a recently developed composite tool for scoring disease activity in juvenile idiopathic arthritis (JIA). JADAS consists of four items; the joint count, the physician and the patient’s/parent’s global assessment and the erythrocyte sedimentation rate (ESR) as an inflammatory marker. Creactive protein (CRP) has been suggested as an a...

Background: Psoriasis is associated with premature atherosclerosis and cardiovascular co-morbidity and mortality. Objective: To determine endothelial function in severe psoriasis at onset compared to that of matched healthy controls Methods: Using high-resolution ultrasound, we measured the diameter of brachial artery at rest, during reactive hyperemia, and after sublingual nitroglycerin. We co...

C-reactive protein (CRP) has become the subject of avid interest in recent years, but the history of CRP began > 7 decades ago and has been one of discovery and continuing dispute. In 1930, Tillet and Francis1 observed a substance in the serum of people with pneumococcal infections that formed a precipitate when mixed with the C-polysaccharide coat of Streptococcus pneumoniae. This “Creactive” ...

Damirchi A, Rahmani-Nia F, Mehrabani J. Lipocalin-2: Response to a short-term treadmill protocol in obese and normal-weight men. J. Hum. Sport Exerc. Vol. 6, No. 1, pp. 59-67, 2011. Background: Lipocalin-2 (Lcn2) a newer adipocyte-secreted acute phase protein was recently reported to be correlated with potential effects in obesity and inflammation. The reactions of this protein in progressive e...

Introduction: Association between plasma high-sensitivity C-reactive protein (CRP) concentrations and cardiovascular disease has been Investigated. C-reactive protein (CRP) is an acute phase reactant which is a marker of inflammation in the body. CRP is made by the liver in response to inflammatory cytokines such as interleukin-6 (IL-6) and tumor necrosis factor-α (TNFα). Adipose tissue is a ma...