Hereditary hypophosphatemic rickets (HHR) are a group of diseases characterized by renal phosphate wasting causing growth retardation, rickets and osteomalacia. The most common form is the X-linked dominant hypophosphatemic rickets caused by inactivating mutations in the PHEX gene. The other hereditary hypophosphatemic syndromes present a lower prevalence. These include autosomal dominant hypop...

Abstract The effect of soil moisture (SM) on precipitation is an important issue in the land–atmosphere interaction and shows largely regional differences. In this study, SM ERA-Interim reanalysis data weather stations were used to investigate their relationship over eastern China during July August. Moreover, WRF model was applied further validate rainfall. observations, a significantly negati...

Much has been written recently in the popular press about rise of sports gambling, historical horse racing or instant (HHR), and esports. However, despite this, some note an overall decline popularity gambling gaming general as (pari-mutuel) wagering declined dramatically over decades casino lottery revenues have fallen slightly since before Great Recession. This exploratory research examines t...

BACKGROUND Demand for rehabilitation services is expected to increase due to factors such as an aging population, workforce pressures, rise in chronic and complex multi-system disorders, advances in technology, and changes in interprofessional health service delivery models. However, health human resource (HHR) strategies for Canadian rehabilitation professionals are lagging behind other profes...

Naturally occurring regulatory T cells (nTregs), important for immune regulation and the maintenance of self-tolerance, develop in the thymus. The Hirosaki hairless rat (HHR), derived from the Sprague-Dawley rat (SDR), was shown to have decreased peripheral lymphocyte number, small thymus, and leukocyte infiltration in its dermis. In the HHR thymus, the medulla was underdeveloped and nTreg numb...

Examples of small self-cleaving RNAs embedded in noncoding regions already have been found to be involved in the control of gene expression, although their origin remains uncertain. In this work, we show the widespread occurrence of the hammerhead ribozyme (HHR) motif among genomes from the Bacteria, Chromalveolata, Plantae, and Metazoa kingdoms. Intergenic HHRs were detected in three different...

Two plasmids were discovered in the ammonia-oxidizing bacterium Nitrosomonas sp. strain ENI-11, which was isolated from activated sludge. The plasmids, designated pAYS and pAYL, were relatively small, being approximately 1.9 kb long. They were cryptic plasmids, having no detectable plasmid-linked antibiotic resistance or heavy metal resistance markers. The complete nucleotide sequences of pAYS ...

Endoprosthetic reconstruction after bone tumor resection is accepted treatment for femoral tumors. The objective of this study is to evaluate the effectiveness and functional outcomes of custom prosthetic replacement of the proximal femur in patients undergoing oncologic resection. Data of 28 consecutive patients with proximal femur tumors receiving wide resection and prosthetic replacement (16...

Many studies examine the impact of interprofessional (IP) interventions on various health practice and education outcomes. One significant gap is the lack of research on the effects of IP interventions on health human resource (HHR) outcomes. This project synthesized the literature on the impact of IP interventions at the pre- and post-licensure levels on quality workplace, staff satisfaction, ...

Research into river processes in different climatic and geomorphic areas is vital for a clearer understanding of the non-linear responses rivers to climate change. The Huaihe River (HHR) Basin, located China’s North–South Transition Zone (NSTZ), provides an ideal environment which explore change within humid/semi-humid transitional area. Based on optically stimulated luminescence (OSL) 14C dati...