Mosquitoes are vectors of several human pathogens, and great attention has recently been placed on insecticides from plant-derived products, in search for mosquito control agents. This study, thus, investigated the potency of Boswellia dalzielii methanol leaf extract and its four fractions as mosquito ovicide, larvicide, and pupicide against Anopheles gambiae and Culex quinquefasciatus. The pla...

The methanolic extract along with some organic soluble fractions of the bark of Dillenia indica Linn. were tested against four Gram-positive and seven Gram-negative bacteria and against three pathogenic fungi. n-Hexane and dichloromethane fractions showed remarkable activities against all the tested bacteria but n-Hexane fraction showed highest activity against Shigella dysenteriae and its zone...

Column chromatography of the Egyptian date palm pollen, resulted in the isolation of estradiol, estrone among ten compounds from the hexane fraction. Also, besides rutin, additional four flavonoids from the ethyl acetate extract were isolated. HPLC analysis of the hexane fraction (using RFBDS C18 – isocratic acetonitrile /water 58:42) revealed the presence of estrone, estradiol and estriol comp...

This study evaluated the anti-inflammatory effect of Kaempferia galanga (KG) using an activity-guided approach. KG rhizomes were serially extracted with petroleum ether, chloroform, methanol and water. These extracts (2 g/kg each) were tested for their ability to inhibit carrageenan-induced rat paw edema. The chloroform extract was found to exert the highest inhibition (42.9%) compared to contr...

with 300 ml of ^2-hexane. The water-alcohol fraction was extracted twice with 300ml of CH2C12and the active CH2C12 extracts concentrated to yield 600mg. The extract was chromatographed on a silica gel column using hexane EtOAcas eluting solvent. Fractions with antitumor activity (280 mg) were eluted with w-hexane EtOAc 75 : 25. Column chromatography on silica gel was repeated and the activity (...

Pulicaria is a genus of flowering plant in the Asteraceae family. It contains over 100 species. In this study the crude extract was prepared from the fresh leaves of P. glutinosa and further fractionated into three solvent to solvent fractions. The zebrafish (Danio rerio) embryos were treated with these extracts to explore the developmental toxicity. The crude extract did not show any significa...

Curcuma xanthorrhiza (CX) has been used for centuries in traditional system of medicine to treat several diseases such as hepatitis, liver complaints, and diabetes. It has been consumed as food supplement and "jamu" as a remedy for hepatitis. Hence, CX was further explored for its potential as a functional food for liver related diseases. As such, initiative was taken to evaluate the antioxidan...

Irvingia malayana has been utilized for traditional medicine in West Kalimantan, Indonesia.The aim of this research is to detect cytotoxic activity of extract of Irvingia malayana. The extraction with methanol and partition by variated eluen polarity. This extraction produced methanol extract, n-hexane fraction, methylene chloride fraction, ethylacetate fraction and methanol fraction. Cytotoxic...

The incidence of resistance to commonly used antimicrobial agents by microbial pathogens demands increased effort in the development of effective ways of treating infections and diseases. The n-hexane fraction of lyophilized crude bark extract of Parkia biglobosa (Jacq.) was prepared and, in combination with selected antibiotics, assayed for antimicrobial activity against some selected bacteria...

Curcuma aromatica is a plant belonging to genus Curcuma of family Zingiberaceae and is widely used as supplements in Japan. Rhizomes of C. aromatica have curcumin as a major yellow pigment and curdione as a main ingredient of essential oils. In this study, we investigated the affect of C. aromatica on CYP3A4 using 1α,25-(OH)(2)-D(3)-treated Caco-2 clone cells. Caco-2 cells were treated with met...