نتایج جستجو برای: hexahydroquinoline

تعداد نتایج: 68  

Journal: :Acta Crystallographica Section E Structure Reports Online 2012

Journal: :Molecular pharmacology 2014
Brian D Hudson Elisabeth Christiansen Hannah Murdoch Laura Jenkins Anders Højgaard Hansen Ole Madsen Trond Ulven Graeme Milligan

Analysis of the roles of the short chain fatty acid receptor, free fatty acid 3 receptor (FFA3), has been severely limited by the low potency of its endogenous ligands, the crossover of function of these on the closely related free fatty acid 2 receptor, and a dearth of FFA3-selective synthetic ligands. From a series of hexahydroquinolone-3-carboxamides, we demonstrate that 4-(furan-2-yl)-2-met...

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