Thrombophilia can thus be defined as: an inherited or acquired abnormality of haemostasis predisposing to thrombosis, predominantly on the venous side. Although thrombophilia is usually reserved for the hereditary types of hypercoagulability, the antiphospholipid syndrome is generally included under this term and can cause either venous or arterial thrombosis. (Refer to Table 3 for recommendati...

It is now possible to identify acquired and hereditary risk factors in a substantial percentage of patients presenting with a venous thrombotic event. Discovery of the factor V Leiden and prothrombin G20210A mutations has greatly increased the percentage of patients in whom venous thrombosis can be attributed to hereditary thrombophilia. There is, however, considerable uncertainty as to how thi...

Abstract Leading cause of death in pregnant women still remains venous thromboembolism, with an incidence 1.4 to 4.9 per 100,000 pregnancies. A special group inherited and acquired coagulation disorders associated a susceptibility thrombosis is thrombophilia. Physiological changes during the pregnancy also contribute occurrence thromboembolic diseases (VTE) pregnancy. Total rate thromboembolism...

Aim: To compare the D-Dimer levels in patients with mild COVID-19 disease and without hereditary thrombophilia.
 Material Method: Factor V Leiden (G1691A) mutation, methylene tetrahydrofolate gene mutation (C677T, A1298C), PAI-1 (4G-5G) FXIII (V34L) mutations were examined all included study for various reasons such as recurrent miscarriage venous embolism. Patients any thrombophilia group...

thrombophilia increases the incidence of pulmonary thrombosis significantly. various hereditary and acquired factors are known for thromboembolism. the hereditary factors are two common genetic autosomal mutations including factor v leidan mutation and prothrombin gene mutation. a descriptive- analytical design was conducted on 60 patients with thromboembolism who met the inclusion criteria. tw...

Although hypercoagulable states are most often associated with venous thromboses, arterial thromboses are reported in protein C, protein S, antithrombin deficient patients and in those with factor V Leiden, components of hereditary thrombophilia. Because these arterial thromboses (peripheral artery disease, myocardial infarction, and cerebral infarction) mostly affect young persons, aged below ...