نتایج جستجو برای: hepacivirus

تعداد نتایج: 138  

Journal: :Journal of virology 2013
Michael Lauck Samuel D Sibley James Lara Michael A Purdy Yury Khudyakov David Hyeroba Alex Tumukunde Geoffrey Weny William M Switzer Colin A Chapman Austin L Hughes Thomas C Friedrich David H O'Connor Tony L Goldberg

GB virus B (GBV-B; family Flaviviridae, genus Hepacivirus) has been studied in New World primates as a model for human hepatitis C virus infection, but the distribution of GBV-B and its relatives in nature has remained obscure. Here, we report the discovery of a novel and highly divergent GBV-B-like virus in an Old World monkey, the black-and-white colobus (Colobus guereza), in Uganda. The new ...

Journal: :hepatitis monthly 0
krzysztof domagalski department of infectious diseases and hepatology, nicolaus copernicus university, bydgoszcz, poland; department of plant physiology and biotechnology, nicolaus copernicus university, torun, poland małgorzata pawlowska department of infectious diseases and hepatology, nicolaus copernicus university, bydgoszcz, poland; department of infectious diseases and hepatology, nicolaus copernicus university, bydgoszcz, poland. tel/fax: +48-523255605 andrzej tretyn department of plant physiology and biotechnology, nicolaus copernicus university, torun, poland; centre for modern interdisciplinary technologies, nicolaus copernicus university, torun, poland waldemar halota department of infectious diseases and hepatology, nicolaus copernicus university, bydgoszcz, poland malgorzata tyczyno department of infectious diseases and hepatology, nicolaus copernicus university, bydgoszcz, poland dorota kozielewicz department of infectious diseases and hepatology, nicolaus copernicus university, bydgoszcz, poland

background three single nucleotide polymorphisms (snps) near interleukin-28b (il-28b) gene were shown to be highly associated with treatment response (svr) in patients with chronic hepatitis c virus (hcv) infection. there is limited data about the role of single and combined il-28b polymorphisms in hcv-infected polish population. objectives this study's aim was to determine predictability of th...

Journal: :hepatitis monthly 0
moataza h. omran microbial biotechnology department, genetic engineering division, national research centre, dokki cairo, egypt; microbial biotechnology department, genetic engineering division, national research centre, dokki cairo, egypt. tel: +20-1223735450, fax: +20-233370931 wael nabil microbial biotechnology department, genetic engineering division, national research centre, dokki cairo, egypt samar s. youssef microbial biotechnology department, genetic engineering division, national research centre, dokki cairo, egypt mervat el-sayed chemistry department, faculty of science, cairo university, dokki cairo, egypt mostafa k. el awady microbial biotechnology department, genetic engineering division, national research centre, dokki cairo, egypt

results the present work figured out that the heterogeneity of the quasispecies of our local strains 4a was high showing up 15% diversity. this study also showed four glycosylation sites that play an important role in the entry of the virus and protein folding. besides, different epitpoes were identified in different regions of the e1 and e2 domains; a finding which would help in determining th...

2017
Peter Simmonds Paul Becher Jens Bukh Ernest A Gould Gregor Meyers Tom Monath Scott Muerhoff Alexander Pletnev Rebecca Rico-Hesse Donald B Smith Jack T Stapleton

The Flaviviridae is a family of small enveloped viruses with RNA genomes of 9000-13 000 bases. Most infect mammals and birds. Many flaviviruses are host-specific and pathogenic, such as hepatitis C virus in the genus Hepacivirus. The majority of known members in the genus Flavivirus are arthropod borne, and many are important human and veterinary pathogens (e.g. yellow fever virus, dengue virus...

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