Objective: Despite the high prevalence of hemoglobinopathies (HBP), most common single-gene disorders in Turkey, data some regions are lacking. 
 We aimed to evaluate effectiveness hemoglobinopathy premarital screening program (PMS) and investigate contribution efficient use complete blood count (CBC) parameters on cost-effectivity.
 Method: Hemoglobinopathy diagnosed 49171 subjects 4...

Sickle cell disease (SCD), an inherited hemoglobinopathy that causes anemia, severe pain, vaso-occlusive crisis (VOC), is currently recognized as a global public health concern, being the leading cause of pediatric stroke. Our aim was to synthesize evidence on efficacy and safety interventions for managing SCD in this population.

β-Thalassemias and abnormal hemoglobin variants are among the most common hereditary abnormalities in humans. Molecular characterization of the causative genetic variants is an essential part of the diagnostic process. In geographic areas with high hemoglobinopathy prevalence, such as the Mediterranean region, a limited number of genetic variants are responsible for the majority of hemoglobinop...

abstract background iron overload is the main transfusion related side effects in patients with transfusion dependent hemoglobinopathies. severe iron deposition in tissues leads to organ dysfunction. many organs can be affected such as heart, liver, and endocrine organs. cardiac failure and liver fibrosis are the consequent of iron overload in transfusion dependent hemoglobinopathy. magnetic re...

In SC hemoglobinopathy, a rare type of sickle cell disease, patients may experience vaso-occlusive phenomena, but in milder condition than the SS form, considered classic and most common among them. This current study aims to present case patient with this form who received late diagnosis, its clinical evolution, including symptoms, treatment life expectancy based on literature, mainly how is c...