Protective effect was evaluated in streptozoticin (STZ)-induced diabetes rats. 2-Hydroxy 4-methoxy benzoic acid (HMBA) was isolated from the roots of Hemidesmus indicus and administered (500 microg/kg body weight) orally for 7 weeks to STZ-induced diabetic and non-diabetic rats to study its effect on protein metabolism, serum electrolytes and on liver and kidney lipid peroxides. Oral administra...

In the present research two herbal formulations were compared with clindamycin 1% w/w ointment for anti acne activity on acne causing bacteria Propionibacterium acnes and Staphylococcus epidermidis. The herbal formulation (Purodil gel) contains extract of Garcinia indica, Syzygium aromaticum, Glycyrrhiza glabra, Citrus limon, Azadirachta indica, Aloe vera, Hemidesmus indicus, Acorus calamus, Co...

AIM: This study was conducted to study the hepatoprotective property of Hemidesmus indicus (L.) R.Br. roots. METHODS: Hepatoprotective properties of the methanol extract of the roots of H. indicus var. pubescens were evaluated on paracetamol induced hepatotoxicity. Hepatotoxicity was induced in albino Wistar rats by the administration of paracetamol (1g/kg), p.o. for 7 days. Methanol extract of...

The larvicidal activities to determine the efficacies of acetone, ethyl acetate, chloroform and butanol dried leaf extracts of Annona squamosa, Cynodon dactylon, Melia azedarach and root extract of Hemidesmus indicus tested against 3 instar Culex quinquefasciatus and Aedes aegypti. The highest larvae mortality was found in the acetone followed by ethyl acetate, chloroform and butanol extract of...

Objective: To analyse the antidiarrhoeal activity of Hemidesmatus indicus (L) R. Br root aqueous (HIRAE) and ethanolic (HIREE) extracts. Methods: HIRAE and HIREE at the dose of 100 and 200mg/kg bw was used to assess antidiarrheal activity in albino rats. Antidiarrheal activity was studied with reference to castor oil diarrhea for assessing faecal score, intestinal transit and enteropooling and ...

Capsicum annum L. (Family: Solanaceae) and Hemidesmus indicus (Linn.) R.Br. (Family: Asclepiadaceae) are commonly used in Tamilnadufor treating various ailments in the native system of medicine. The hydroalcoholic extracts of both plants at dose level of 100 mg/kg body weight showed demonstrable anti-inflammatory activity in the carrageenan-induced hind paw model in rats. Nevertheless, the over...

The roots of Decalepis hamiltonii and Hemidesmus indicus are aromatic and possess the crystalline compound 2-hydroxy-4-methoxybenzaldehyde as the major compound (> 90%) in their volatile oils. A gas chromatographic procedure was developed for the assay of 2-hydroxy-4-methoxybenzaldehyde in both fresh and dried roots of different origin. Benzyl butyrate was used as the internal standard. Among t...