Clonal non-malignant hematological disorders are a heterogeneous group of diseases that are particularly challenging for hematologists. Indeed, most obvious and frequent hematological diseases include a broad spectrum of malignancies, such as leukemias, lymphomas, myeloma, and other myeloproliferative or lymphoproliferative disorders. In recent years, all these diseases have been categorized by...

The huge amount of experimental and clinical observations supporting the possible involvement of human herpesvirus 8 (HHV-8) or Kaposi sarcoma herpesvirus (KSHV) in human lymphoproliferative diseases was critically reviewed during a workshop organized by the Italian Society for Experimental Hematology in Florence, Italy, on July 3rd, 1997. The organizers have prepared this report for the reader...

Objective(s): Over the past 20 years, increasing interest in the use of medicinal plants as alternative or adjuvant treatments of several chronic diseases was observed. Accordingly, Nigella sativa or black cumin, a medicinal plant rich in bioactive compounds, has been used worldwide for food purposes or in traditional medicines. This paper aims to reveal N. sativa pote...

Autoimmune diseases (ADs) have close relationship with the onset of malignant lymphoma. They closely tie to lymphoma. Immune disorders might play an important role in transformation from ADs to lymphoma. DLBCL occurred after autoimmune hematological diseases and autoimmune lymphoproliferative syndrome (ALPS) was rare. The interval between ADs and DLBCL was long and the pathogenesis might be rel...

BACKGROUND/AIM Pancytopenia is caused by acute myeloid leukemia (AML), myelodysplastic syndrome (MDS), aplastic anemia (AA), or by non-hematological diseases. Because Wilms' tumor-1 (WT1) is overexpressed in patients with AML and MDS, its expression level may be helpful for diagnosing these hematological malignancies. PATIENTS AND METHODS We retrospectively investigated the WT1 transcripts in...