نتایج جستجو برای: helix pomatia agglutinin
تعداد نتایج: 29327 فیلتر نتایج به سال:
BACKGROUND The pathological classification of cryptogenic fibrosing alveolitis has been a matter of debate and controversy for histopathologists. OBJECTIVE To identify and specify the glycotypes of capillary endothelial cells in usual interstitial pneumonia (UIP) compared to those found in normal tissue. METHODS Sections of formalin-fixed, paraffin-embedded blocks from 16 cases of UIP were ...
Altered glycosylation of proteins in cancer cells is one of the main processes responsible for anaplasia, invasion and metastatic potential of neoplastic cells. Lectins are nonimmunogenetic compounds which specifically detect certain terminal sugars of glycoconjugates. The aim of the present study was to identify the N-acetylgalactosamine (GalNac) containing glycoconjugates in cancer cells in a...
Carbohydrates participate in almost every aspect of biology from protein sorting to modulating cell differentiation and cell-cell interactions. To date, the majority of data gathered on glycan expression has been obtained via analysis with either anti-glycan antibodies or lectins. A detailed understanding of the specificities of these reagents is critical to the analysis of carbohydrates in bio...
Objetive. This study was conducted to evaluate, by means of lectinhistochemistry (LHC), the expression of carbohydrates in granulomas induced by the bacillus Calmette-Guerin (BCG) in muscle tissue of Piaractus mesopotamicus after 33 days. Material and methods. Histological sections with 3 μm thick were incubated with the following lectins :WGA (Wheat germ agglutinin), DBA (Dolichos biflorus agg...
BACKGROUND The group-specific component protein-derived macrophage-activating factor (GcMAF) has various biological activities, such as macrophage activation and antitumor activity. Clinical trials of GcMAF have been carried out for metastatic breast cancer, prostate cancer, and metastatic colorectal cancer. In this study, despite the complicated purification process of GcMAF, we used enzymatic...
BACKGROUND Gc protein has been reported to be a precursor of Gc protein-derived macrophage activation factor (GcMAF) in the inflammation-primed macrophage activation cascade. An inducible beta-galactosidase of B cells and neuraminidase of T cells convert Gc protein to GcMAF. MATERIALS AND METHODS Gc protein from human serum was purified using 25(OH)D3 affinity column chromatography and modifi...
BACKGROUND/AIM Colostrum contains antibodies, such as immunoglobulin G (IgG), immunoglobulin A (IgA) and immunoglobulin M (IgM), and, therefore, has potent immunomodulating activity. In particular, IgA has an O-linked sugar chain similar to that in the group-specific component (Gc) protein, a precursor of the Gc protein-derived macrophage-activating factor (GcMAF). In the present study, we inve...
AGGLUTININ (HPA): A HEXAMERIC LECTIN WITH A NOVEL FOLD* Jean-Frederic Sanchez, Julien Lescar, Valérie Chazalet, Aymeric Audfray, Jean Gagnon, Richard Alvarez, Christelle Breton, Anne Imberty & Edward P. Mitchell From Centre de Recherches sur les Macromolécules Végétales, CNRS (affiliated with Université Joseph Fourier), Grenoble, France, School of Biological Sciences, Nanyang Technological Univ...
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