Background: Resistance to antibiotics, including aminoglycosides  (AMG) is one of the problems associated with inappropriate administration of broad-spectrum antibiotics. Objectives: This study aimed to assess the clinical features of aminoglycosides consumption based on the Defined Daily Dose (DDD) index in open heart surgery. Methods: This study was done on 268 patients who underwent heart s...

OBJECTIVE The purpose of the work was to estimate the dose received by the heart throughout a course of breath-holding breast radiotherapy. METHODS 113 cone-beam CT (CBCT) scans were acquired for 20 patients treated within the HeartSpare 1A study, in which both an active breathing control (ABC) device and a voluntary breath-hold (VBH) method were used. Predicted mean heart doses were obtained...

background: methyl 2-benzimidazole carbamate (carbendazim) is a synthetic fungicide used against organisms that cause different types of plant diseases. it is widely used as a preservative in leather, paint, textile, fruit, and paper industry. it is also used as an anticancer drug in clinical medicine. methods: to evaluate the low dose toxicity of this compound in mammalian tissues, carbendazim...

Elevated sympathetic tone and b-AR desensitization are characteristics associated with heart failure (HF) contributors to the initiation of arrhythmia. Studies have shown that altered responsiveness in HF leads compartmentalization imparied sub-cellular cAMP signaling. Yet, if signaling is heterogeneously remodeled throughout intact heart, how this may contribute arrhythmia unknown. To assess w...

Cardiac irradiation increases the risk of coronary artery disease in patients with left-sided breast cancer. Techniques exist to reduce cardiac irradiation, but the optimum technique depends on individual patient anatomy and physiology. We investigated the correlation of delta heart volume in field (dHVIF) and sternal excursion with dose sparing in heart and left anterior descending artery (LAD...