this a case report of an iranien jewish young women, who had hypochromic anemia inspitc of incrcscd medullary iron.. this finding lead to the discovery of hb h in one of her sister's and one of her daughters, who (like beta thalassemia trait), but presence of hb h in her sister and daughter, and presence of minimum quantities of bart's hb in her sister.

Hats off to you and your sister for recognizing that nutrition needs change in teenagers as their bodies mature, especially during puberty. The good news is that a well-planned vegetarian diet that includes key nutrients (keep reading for specifics) can be supportive of health at all stages of life and won?t inhibit growth or bone health. Beyond focusing on what you eat though, having support f...

Sister Mary, the gold standard for the Nun Study, was a remarkable woman who had high cognitive test scores before her death at 101 years of age. What is more remarkable is that she maintained this high status despite having abundant neurofibrillary tangles and senile plaques, the classic lesions of Alzheimer's disease. Findings from Sister Mary and all 678 participants in the Nun Study may pro...

PURPOSE To describe a new mutation of the trabecular meshwork-inducible glucocorticoid response protein (TIGR) gene in a Japanese patient with familial primary open angle glaucoma (POAG). METHODS Standard ocular examinations were performed on the 44-year-old patient, his sister, and mother. DNA sequencing was used to identify the mutation. We also developed a DNA diagnostic method for detecti...

Aneuploidy in human eggs is the leading cause of pregnancy loss and Down's syndrome. Aneuploid eggs result from chromosome segregation errors when an egg develops from a progenitor cell, called an oocyte. The mechanisms that lead to an increase in aneuploidy with advanced maternal age are largely unclear. Here, we show that many sister kinetochores in human oocytes are separated and do not beha...