Cleavage stimulation factor (CstF) is a heterotrimeric protein complex essential for polyadenylation of mRNA precursors. The 77 kDa subunit, CstF-77, is known to mediate interactions with the other two subunits of CstF as well as with other components of the polyadenylation machinery. We report here the crystal structure of the HAT (half a TPR) domain of murine CstF-77, as well as its C-termina...

‎In this paper we investigate the dilations of completely positive definite representations‎ ‎of (C^ast)-dynamical systems with abelian groups on Hilbert (C^ast)-modules‎. ‎We show that if ((mathcal{A}‎, ‎G,alpha)) is a (C^ast)-dynamical system with (G) an abelian group‎, ‎then every completely positive definite covariant representation ((pi,varphi,E)) of ((mathcal{A}‎, ‎G,alpha)) on a Hilbert ...

The mexican hat function is used to model a compensated (in density) gravitational lens. First we discuss the need for compensation. Then we integrate photon orbits to construct wavefronts. One consequence of underdensities is an o -axis caustic. We report the structure of the critical curves and caustics using the thin lens approximation, both for the mexican hat and for a perturbed mexican ha...

We present an exact solution to the problem of the global shape description of a spherical vesicle distorted by a grafted latex bead. This solution is derived by treating the nonlinearity in bending elasticity through the (topological) Bogomol'nyi decomposition technique and elastic compatibility. We recover the "hat-model" approximation in the limit of a small latex bead and find that the regi...

The bowler-hat sign has been described both with colonic polyps and with diverticula. The authors describe a simple principle for evaluating a bowler-hat sign in order to determine whether it is caused by a polyp or a diverticulum. If the bowler hat points toward the center of the long axis of the bowel, it represents an intraluminal structure (ie, a polyp). If, however, it points away from the...