We develop an easy-to-implement method for forecasting a stationary autoregressive fractionally integrated moving average (ARFIMA) process subject to structural breaks with unknown break dates. We show that an ARFIMA process subject to a mean shift and a change in the long memory parameter can be well approximated by an autoregressive (AR) model and suggest using an information criterion (AIC o...

This paper addresses the problem of fast Human Activity Recognition (HAR) in visual lifelogging. We identify the importance of visual features related to HAR and we specifically evaluate the HAR discrimination potential of Colour Histograms and Histogram of Oriented Gradients. In our evaluation we show that colour can be a low-cost and e↵ective means of low-cost HAR when performing single-user ...

A specific quantitative real-time PCR (qPCR) method was developed for the quantification of hepatotoxin nodularin-producing Nodularia, one of the main bloom-forming cyanobacteria in the Baltic Sea. Specific PCR primers were designed for subunit F of the nodularin synthetase gene (ndaF), which encodes the NdaF subunit of the nodularin synthetase gene complex needed for nodularin production. The ...

ISIS är ett centrum med nio industripartners och sex forskningsgrupper, med inriktning mot industriella styroch övervakningsproblem, och med syfte att använda och utveckla verktyg b̊ade fr̊an datavetenskap och reglerteknik. De största utmaningarna för ett kompetenscentrum är att h̊alla en bra balans mellan vetenskaplig production och industriellt relevans, att producera välutbildade personer och a...

We examine the informational content of historical and implied measures of variance through an evaluation of forecasts over horizons ranging from 1 to 22 days. These forecasts use heterogeneous autoregressive (HAR) regressions which are constructed with high-frequency data. Our results show that the t and forecasting ability of models based on historical realized variance (RV) increases with th...

Harmaline (HAR), a natural occurrence β-carboline alkaloid, was isolated from the seeds of Peganum harmala and exhibited potent antitumor effect. In this study, the anti-gastric tumor effects of HAR were firstly investigated in vitro and in vivo. The results strongly showed that HAR could inhibit tumor cell proliferation and induce G2/M cell cycle arrest accompanied by an increase in apoptotic ...

Autoregulation is a control mechanism common to several proteins of the steroid/thyroid hormone receptor superfamily. In this work, the effect of androgens and antiandrogens on the expression of the human androgen receptor (hAR) in prostate and breast cancer cell lines was studied. Northern blot analysis revealed a decrease in hAR steady state RNA levels in LNCaP cells by 3.3 nM of the syntheti...

Gobind Khorana was a scientist who traversed boundaries, both scientifically and culturally. He pioneered the use of concepts and tools from chemistry and physics to tackle fundamental questions of biology. In particular, he helped to decipher how RNA encodes for the synthesis of protein, research that earned him the Nobel Prize in Medicine with Marshall Nirenberg and Robert Holley in 1968. Alt...

Aldose reductase (AR), an enzyme mediating the first step in the polyol pathway of glucose metabolism, is associated with complications of diabetes mellitus and increased cardiac ischemic injury. We investigated whether deleterious effects of AR are due to its actions specifically in cardiomyocytes. We created mice with cardiac specific expression of human AR (hAR) using the α-myosin heavy chai...

Iron ore future has an extreme influence on global financial markets. Thus, we are supposed to consider the day-of-the-week effect, which is important volatility of iron price, although less existing literature considers it. The effect added basic heterogeneous autoregressive (HAR) model so that a new type established. empirical results show higher accuracy in forecasting price and contains muc...